Project Grant R15EB040449
- The National Institute of Biomedical Imaging and Bioengineering awarded the Board of Trustees of Illinois State University $553,931 on August 25, 2026, for development of a surface-enhanced Raman scattering (SERS)-based rapid vertical flow assay (RVFA) for point-of-care diagnostic testing under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286). The award funds research to advance infectious disease diagnostics by improving analytical...
- Federal Grant Award Summary Colorado State University received a $413,067 Project Grant from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), effective September 1, 2025, through August 31, 2027. The project aims to develop an improved class of electrochemical biosensors utilizing engineered binding proteins to simplify electrode fabrication and enhance...
- The National Institute of Biomedical Imaging and Bioengineering awarded $182,558 to Iowa State University of Science and Technology on May 6, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop a bioinspired drug discovery strategy for personalized combination immunoregulatory therapeutics. The research leverages the foreign body response within subcutaneous biomaterial scaffold implants to identify...
- The National Institute of Allergy and Infectious Diseases awarded the Board of Trustees of Southern Illinois University $547,292 on September 1, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to develop a rapid diagnostic system for bacteremia pathogen identification and antimicrobial susceptibility testing. The project integrates immunocapture, microfluidics, and artificial intelligence to detect bacteria directly from blood samples at low concentrations (1–103...
- The National Institute of Biomedical Imaging and Bioengineering awarded the University of Cincinnati Sponsored Research Services Division $398,400 on September 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop chemically-modified aptamer electrochemical sensors for ultra-sensitive biomonitoring. The research advances continuous biochemical monitoring technology to detect biomarkers at picomolar-to-nanomolar...
- The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $359,995 Project Grant under the "Discovery and Applied Research for Technological Innovations to Improve Human Health" (CFDA 93.286) program to Clemson University. The funding supports the development and validation of a novel X-ray visualized immunosensor (X-VIS) that can be attached to implanted medical devices to detect and monitor local infection biomarkers. The project aims to fabricate a...
- Federal Grant Award Summary The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded the University of Missouri System $418,043 under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) for a two-year project grant running from August 1, 2025, through July 31, 2027. The project deliverables center on the design and development of a self-tunable messenger RNA (mRNA) circuit capable of sustained, precise regulation...
- The National Institute of General Medical Sciences awarded The Ohio State University $382,823 on July 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop a label-free analytical method for imaging biomarker distribution in soft tissues. The project introduces silicon-based light-enabled active potentiometry (SILEAP), a mechanically flexible, ultrathin electronic interface constructed from an unpatterned SiO₂/Si bilayer designed to enable spatially...
- The National Institute of Biomedical Imaging and Bioengineering awarded the University of Illinois $226,160 on August 17, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to engineer virus-like particles (VLPs) for systemic and targeted RNA delivery to the brain across the blood-brain barrier. The project will develop and optimize VLPs capable of efficient, brain-targeted RNA delivery by engineering them to recognize...
- The National Institute of General Medical Sciences awarded the Board of Trustees of Southern Illinois University $248,901 on September 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to purchase a BD FACSMelody high-speed cell sorter equipped with blue, red, and violet lasers for use by biomedical researchers at Southern Illinois University–Carbondale. The instrument will serve investigators across two SIUC colleges and the SIU School of Medicine conducting...
The National Institute of Biomedical Imaging and Bioengineering awarded the Board of Trustees of Southern Illinois University $556,875 on September 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to support undergraduate-led research on an electrografted molybdenum disulfide immunosensor. The research establishes the first solid-state electrografted interface combining covalently linked antibody probes and two-dimensional molybdenum disulfide (MoS₂) transducers for immunosensing applications. The project addresses a gap in existing MoS₂-based biosensing, which relies on adsorption strategies prone to probe desorption, random orientation, and inconsistent density. The two main objectives are synthesizing and characterizing the covalently tethered antibody-MoS₂ interface, and systematically investigating label-free charge transduction at this interface for detecting neurodegenerative biomarkers in body fluids. The study examines variables influencing interface stability, charge transduction, and sensing capabilities including robustness, sensitivity, and selectivity in complex media such as serum. Work is performed in Carbondale, Illinois. The period of performance runs from September 1, 2026, through August 31, 2029. This is a Project Grant, a form of assistance funding supporting hypothesis-driven research related to discovery, design, development, and validation of biomedical imaging and bioengineering technologies.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $556.9k | 8/13/26 |