Project Grant R15EB039339
- The National Institute of Allergy and Infectious Diseases awarded the Board of Trustees of Southern Illinois University $547,292 on September 1, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to develop a rapid diagnostic system for bacteremia pathogen identification and antimicrobial susceptibility testing. The project integrates immunocapture, microfluidics, and artificial intelligence to detect bacteria directly from blood samples at low concentrations (1–103...
- The National Institute of Biomedical Imaging and Bioengineering awarded the Board of Trustees of Southern Illinois University $556,875 on September 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to support undergraduate-led research on an electrografted molybdenum disulfide immunosensor. The research establishes the first solid-state electrografted interface combining covalently linked antibody probes and...
- The National Science Foundation Division of Chemical, Bioengineering, Environmental, and Transport Systems awarded the University of Illinois $574,042 on August 15, 2026, to develop plasmonic nano-assemblies with fluorescent nanodiamonds and photonic metamaterial enhancement for spectroscopic detection of biomolecules, under the Engineering program (CFDA 47.041). The project will fabricate hybrid nanoassemblies composed of metal nanoparticles and nanodiamonds coupled with photonic crystals to...
- The National Institute of Allergy and Infectious Diseases awarded the University of Illinois $1.506 million on September 16, 2025, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to develop a human factors-designed point-of-care test for simultaneous detection of HIV, HBV, and HCV viral loads in whole blood. The award funds development of a microfluidic cartridge, molecular biology method, biosensor using crumpled graphene readout, and detection instrument capable of...
- The National Science Foundation Division of Chemistry awarded the Board of Trustees of Illinois State University $455,081 on August 1, 2026, under the Mathematical and Physical Sciences program (CFDA 47.049) to support research on nanobody-gold nanoparticle conjugates and their plasmonic properties. Professor Jeremy Driskell's team will develop a strategy to immobilize nanobodies onto gold nanoparticles to form stable conjugates for use as signal-generating plasmonic probes in biotechnology...
- The National Institute of General Medical Sciences awarded the Board of Trustees of Southern Illinois University $248,901 on September 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to purchase a BD FACSMelody high-speed cell sorter equipped with blue, red, and violet lasers for use by biomedical researchers at Southern Illinois University–Carbondale. The instrument will serve investigators across two SIUC colleges and the SIU School of Medicine conducting...
- The National Institute of Allergy and Infectious Diseases awarded the Board of Trustees of Illinois State University $555,000 on June 17, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to investigate the response and defense mechanisms of extraintestinal Escherichia coli to reactive oxygen and chlorine species. The research examines how extraintestinal pathogenic E. coli strains defend against bactericidal host defense mechanisms, specifically reactive oxygen...
- The National Institute of Biomedical Imaging and Bioengineering awarded the University of Rochester $226,625 on September 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop a tandem-chip microphysiological system for assessing cytokine release syndrome and immune effector cell-associated neurotoxicity syndrome in immunotherapy patients. The recipient will engineer an integrated drug development tool...
- The National Institute of General Medical Sciences, a component of the Department of Health and Human Services National Institutes of Health, awarded 37Degrees, Inc. $360,247 on September 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859, assistance type: Project Grant). The award funds development of photoacoustic microscopy systems for non-destructive, three-dimensional imaging of live and incubated engineered tissue. The project addresses a critical gap in...
- The National Institute of General Medical Sciences awarded the University of Illinois $1,385,652 on April 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop in vivo metabolic tagging and targeting of long-circulating red blood cell biomembranes. The project aims to create a platform technology for metabolic tagging of red blood cell (RBC) membranes using unnatural sugars and subsequent targeting of molecular imaging and therapeutic cargo via click...
The National Institute of Biomedical Imaging and Bioengineering awarded the Board of Trustees of Illinois State University $553,931 on August 25, 2026, for development of a surface-enhanced Raman scattering (SERS)-based rapid vertical flow assay (RVFA) for point-of-care diagnostic testing under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286). The award funds research to advance infectious disease diagnostics by improving analytical sensitivity through site-specific immobilization of antibodies on plasmonic nanoparticles and controlled assembly of plasmonic particles. The research will explore a chemo-enzymatic approach to localize and orient capture antibodies on plasmonic paper to maximize SERS signal; conduct SERS analysis of augmented plasmonic nanoparticle assemblies driven by antibody-antigen interactions; and demonstrate simultaneous quantitation of multiple antigens in a multiplexed assay with established quality control parameters. Performance occurs in Normal, Illinois. The period of performance runs through August 24, 2029. The assistance type is a Project Grant.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $553.9k | 8/21/26 |