Project Grant R15EB038729
- The National Institute of Biomedical Imaging and Bioengineering awarded the University of Texas at Dallas $186,674 on August 7, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop fullwave physics-informed recurrent neural networks for ultrasound simulation, quantitative imaging, and adaptive focusing. The project addresses barriers to clinical adoption of quantitative ultrasound by developing a single...
- The National Institute of Biomedical Imaging and Bioengineering (NIBIB), part of the Department of Health and Human Services National Institutes of Health, awarded the University of Texas at Arlington $339,676 on August 18, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop light-responsive osmium compounds as metallo-reagents for biomedical imaging and photoactivation. The project develops osmium-based...
- The National Institute of Biomedical Imaging and Bioengineering awarded the University of Texas at Dallas $486,805 on July 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop margination-mediated delivery and glutathione-triggered release mechanisms enabled by renal-clearable gold nanoparticles for fluorescence-guided surgery of brain metastases. The project addresses a clinical gap: current...
- This $1,634,839 Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences Program (CFDA 47.049) aims to revolutionize live-cell imaging by developing nanodiamond quantum sensors with exceptional sensitivity. The research, titled "QUSEC-TAQS: Nanodiamond Quantum Sensing for Four-Dimensional Live-Cell Imaging", will integrate nanodiamond quantum sensors with advanced light-sheet microscopy to achieve high spatiotemporal resolution and low...
- The National Institute of Biomedical Imaging and Bioengineering awarded Case Western Reserve University $531,541 on April 23, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop contrast-enhanced ultrasound imaging biomarkers for predicting nanoparticle therapeutic accumulation in tumors. The research develops a series of contrast-enhanced ultrasound biomarkers that correspond to increased vascular permeability...
- The National Institute of Biomedical Imaging and Bioengineering, a component of the Department of Health and Human Services National Institutes of Health, awarded $184,063 to the University of Texas at San Antonio on September 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286). The award funds development of forced-dimerization activated photoacoustic aptamer switch sensors (FDA-PASS), optical probes designed to enable...
- The National Institute of General Medical Sciences awarded the University of North Texas $249,200 on July 1, 2026, through the Biomedical Research and Research Training program (CFDA 93.859) to acquire a Fujifilm VisualSonics VEVO F2 LT high-resolution ultrasound imaging system for small-animal research. The system will establish centralized ultrasound imaging capabilities at the university's vivarium, enabling real-time, non-invasive in vivo cardiac and tumor imaging across small-animal...
- The National Institute of Biomedical Imaging and Bioengineering awarded the University of Texas at Dallas $499,156 on June 1, 2026, to develop acoustic blood oxygen level dependent (BOLD) imaging technology for noninvasive bedside monitoring of deep brain tissue oxygenation in neonates with hypoxic brain injury. The recipient will design and validate oxygen-responsive ultrasound contrast agents—specifically hemoglobin-filled microbubbles—that function as biosensors to enable real-time,...
- The National Institute of Biomedical Imaging and Bioengineering awarded Scripps Research Institute $276,000 on August 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop and validate novel fluorescence resonance energy transfer (FRET) sensing methods that leverage entangled photons for biomedical applications. The project will explore quantum sensing technologies to advance FRET-based detection across biological...
- The National Institute of Biomedical Imaging and Bioengineering awarded The University of Texas Southwestern Medical Center $536,853 on September 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286). The award funds development and validation of a comprehensive 7 Tesla MRI framework for simultaneous high-resolution mapping of brain iron and myelin in mesoscale brain structures. The project integrates three complementary...
The National Institute of Biomedical Imaging and Bioengineering awarded Texas Christian University $495,541 on August 18, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop metal-doped graphene quantum dots as dual-mode contrast agents combining ultrasound and near-infrared fluorescence imaging. The research will synthesize and optimize biocompatible metal-doped graphene quantum dots to overcome limitations of current ultrasound contrast agents and conventional fluorophores, addressing clinical need for lower-cost, portable diagnostic approaches with improved stability and imaging depth. The work progresses through three phases: synthesis and structural optimization of the quantum dots for enhanced ultrasound and fluorescence performance; testing in vascular and tissue phantoms; and in vivo imaging in rats to assess biodistribution, evaluate clinical diagnostic targets, and toxicity. The award is classified as a Project Grant. Performance occurs in Fort Worth, Texas, with a period of performance from August 18, 2026, through August 17, 2029.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $495.5k | 8/18/26 |