Project Grant R15AR086481
- The National Institute of Arthritis and Musculoskeletal and Skin Diseases awarded The Trustees of Columbia University in the City of New York $100,228 on November 27, 2026, under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846). The research investigates the mechanotransduction pathways regulating tendon development, specifically the role of MRTF/SRF signaling in response to mechanical cues. The project integrates in vitro models using mouse embryonic stem...
- The National Institute of Arthritis and Musculoskeletal and Skin Diseases awarded The Johns Hopkins University $697,369 on August 5, 2026, under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) to investigate nerve-tendon crosstalk as a mechanism for enhancing tendon repair while mitigating pain-related responses. The project focuses on separating regenerative signaling pathways from pain signaling pathways following tendon injury. Research will examine how nerve...
- The National Institute of Arthritis and Musculoskeletal and Skin Diseases awarded The Regents of the University of Colorado $348,339 on May 1, 2026, under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846). The award funds research on the mechanical role of hyaluronic acid in tendon fibers and how glycosaminoglycan depletion affects strain recovery in collagen. The research employs laser ablation of collagen fibers within intact tendons and enzymatic treatments...
- The National Institute of Arthritis and Musculoskeletal and Skin Diseases awarded the University of Wisconsin–Madison $198,460 on September 15, 2025, under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846). The project, titled "Advancing Rehabilitation of Patellar Tendon Injuries Using Innovative Wearable Technology and Quantitative Magnetic Resonance Imaging Techniques," develops methods to optimize rehabilitation and improve treatment outcomes for...
- The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) awarded Carnegie Mellon University $1.04 million on April 1, 2026, under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) to develop and validate a sensorized compression sleeve for muscle-activity monitoring and rehabilitation tracking in patients following anterior cruciate ligament reconstruction. The research investigates capacitive sensing embedded in e-textiles as a tool to...
- The National Institutes of Health National Institute of Arthritis and Musculoskeletal and Skin Diseases awarded the University of Rochester $493,971 on September 1, 2026, under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) to define the epitenon cell–gamma delta T cell axis in fibrotic tendon healing. The project addresses peritendinous adhesions that form between healing tendons and surrounding tissues, the leading cause of impaired recovery following tendon...
- The National Institute of Arthritis and Musculoskeletal and Skin Diseases awarded Biosensics LLC $314,362 under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) on September 1, 2026, to develop digital assessment tools for motor skills in infants and young boys with Duchenne muscular dystrophy using wearable sensors. The project addresses a critical clinical gap: current motor assessment methods (Bayley Scales of Infant and Toddler Development) cannot detect...
- The National Institute of Arthritis and Musculoskeletal and Skin Diseases awarded the University of Pennsylvania $507,606 on June 1, 2026, under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846, Assistance Listing Project Grant). The research investigates how mechanical loading activates focal adhesion kinase (FAK)-mediated mechanotransduction in tendon cells within their native extracellular matrix environment. The project builds on preliminary findings showing...
- The National Institute of Arthritis and Musculoskeletal and Skin Diseases awarded The Regents of the University of Colorado $578,289 on September 1, 2026, under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846, Assistance Listing R01AR086835). The award funds translation and validation of DualMRI (Displacements Under Applied Loading by MRI), a noninvasive imaging method to measure articular cartilage biomechanics and predict pre-osteoarthritis pathogenesis in...
- The National Institute of Arthritis and Musculoskeletal and Skin Diseases awarded Massachusetts General Hospital $243,192 under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) on November 1, 2025. The award funds research investigating the role of Wnt signaling in the mechanical maturation of postnatal tendon. The research aims to elucidate cellular and molecular mechanisms by which Wnt signaling and Wnt-responsive cellular populations marked by Axin2 expression...
The National Institute of Arthritis and Musculoskeletal and Skin Diseases awarded Brigham Young University $562,975 on September 1, 2026, under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) to quantify Achilles tendon stress in female ballet dancers using shear wave tensiometry and develop tools to prevent tendon injury and support rehabilitation. The project addresses Achilles tendinopathy, which sidelines elite ballet dancers four times more frequently than other athletes. Existing assessment methods lack sensitivity to dancer-specific pain, and direct measurement of tendon stress during dance movements has proven difficult. The research will adapt shear wave tensiometry into a portable, wearable system accommodating the extreme ranges of motion required in ballet en pointe. The study targets female dancers from the BYU Theatre Ballet Company, actively recruiting women while excluding pregnant or lactating participants and male dancers who do not train en pointe. The research aims to establish a scientific foundation for clinicians, pedagogues, and athletes to build training and rehabilitation regimens protecting dancers from injury. The period of performance runs through August 31, 2029, with work conducted in Provo, Utah.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $563.0k | 8/17/26 |