This Project Grant award, funded by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273) federal grant program, aims to investigate the neural mechanisms driving adaptive stress coping behaviors and subsequent alcohol use. The $498,121.57 award, effective August 15, 2024 through July 31, 2027, will utilize an animal model to explore how dysfunction in the corticolimbic circuitry, specifically the prelimbic cortex and basolateral...
This federal Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (NIAAA, CFDA 93.273 Alcohol Research Programs) provides $156,204.00 to the University of Massachusetts Medical School to investigate the role of BNST PKCdelta neurons in compulsive ethanol intake. The key focus is to evaluate adaptations in BNST PKCdelta neuron activity across abstinence periods and in response to ethanol exposure, as well as explore how dysregulation in BNST PKCdelta neuron afferents...
This federal Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (NIAAA), under the Alcohol Research Programs (CFDA 93.273) federal grant program, will support the development of novel 3D human brain circuits to investigate the role of microglia in alcohol use disorder (AUD) and Alzheimer's disease (AD) pathology. The $223,531 award to the University of North Carolina at Chapel Hill will fund research to elucidate how alcohol-induced changes in microglial metabolism...
This federal Project Grant award of $1,135,243 from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273) will support research to investigate changes in neural mechanisms associated with cognitive reappraisal and alcohol cue reactivity during early abstinence from alcohol use disorder (AUD) treatment. The research, conducted by the University of Colorado-Denver and involving sub-awards to Emory University and the University of Denver,...
The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a Project Grant under the Alcohol Research Programs (CFDA 93.273) to The Johns Hopkins University in the amount of $807,050 on August 20, 2024. The grant will fund a research project examining the neural circuit effects of chronic alcohol use on cognition and behavior in rodent models. The key objectives are to: 1) Characterize changes in neural activity within the anterior cingulate cortex, orbitofrontal cortex, and...
This Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (NIAAA), under CFDA Program 93.273 - Alcohol Research Programs, will support research on avoidance learning and pain circuit dysfunction in alcohol use disorders (AUD). The $497,581.76 award, effective September 10, 2024, will enable the principal investigator at Yale University to collect functional MRI data from treatment-seeking AUD patients during a probabilistic learning task involving pain and reward....
This federal Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (NIAAA), under the Alcohol Research Programs (CFDA 93.273) federal grant program, is focused on determining the relationship between rapid ethanol tolerance and sleep regulation in Drosophila (fruit fly) models. The $215,159 award, spanning September 1, 2024 to August 31, 2026, will support three key experiments: 1) mapping rapid ethanol tolerance in sleep circuitry, 2) investigating the labile and...
The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a Project Grant under the Alcohol Research Programs (CFDA 93.273) to the University of Illinois. The $293,128 grant, awarded on August 23, 2024, will fund a study examining the neural correlates of alcohol reward in social contexts using a hyperscanning EEG setup. The research aims to evaluate the neural mechanisms underlying the rewarding effects of alcohol in social settings and assess how individual and group-level factors...
This federal Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (NIAAA), under the Alcohol Research Programs (CFDA 93.273) program, provides $499,442 in funding to The Regents of the University of California, San Francisco (UCSF) from August 20, 2024 through July 31, 2027. The award supports research to investigate the role of brain-derived neurotrophic factor (BDNF) signaling in the ventral hippocampus and its contribution to the acute anxiolytic and social...
This federal Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (NIAAA), under the Alcohol Research Programs (CFDA 93.273), provides $223,932.00 to Trustees of Indiana University, doing business as Indiana University Indianapolis, to conduct research on the neural circuit mechanisms underlying impulsivity and how they are altered by genetic risk for excessive drinking. The key objectives are to: 1) characterize whether dorsomedial prefrontal cortex parvalbumin...