Project Grant R03HL188068
- The National Heart Lung and Blood Institute awarded the Regents of the University of Michigan $234,000 on September 1, 2026, under the Family Smoking Prevention and Tobacco Control Act Regulatory Research program (CFDA 93.077, Assistance Listing 93.077) to examine how the duration of electronic nicotine delivery systems (ENDS) use affects cardiopulmonary health outcomes among adults with current or former cigarette smoking histories. The research leverages prospective, nationally...
- The Department of Health and Human Services National Institutes of Health Office of the Director awarded $821,294 to The Trustees of Columbia University in the City of New York on September 1, 2026, under the Family Smoking Prevention and Tobacco Control Act Regulatory Research program (CFDA 93.077, Project Grant R01HL179303). The award funds the VAPESCAN study, a longitudinal investigation examining early lung toxicity associated with e-cigarette versus cigarette use in young adults aged 18–50....
- The National Heart, Lung, and Blood Institute awarded The Leland Stanford Junior University $718,824 in project grant funding (R01HL188006) on August 1, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837). The award funds research into the mechanisms by which electronic cigarette exposure drives vascular injury and atherosclerosis progression through the glutamate N-methyl-D-aspartate receptor (NMDAR) pathway in vascular smooth muscle cells. The research comprises three...
- The National Institutes of Health National Cancer Institute awarded Cincinnati Children's Hospital Medical Center $694,182 on June 1, 2026, under the Cancer Cause and Prevention Research program (CFDA 93.393) to conduct a prospective longitudinal cohort study examining biomarker levels and respiratory health effects associated with exposure to electronic cigarettes and combustible cigarettes in young children. The research enrolls 300 children ages 1 to 10 years across three equal exposure...
- The National Cancer Institute of the National Institutes of Health awarded the University of Southern California $426,828 on July 6, 2026, through the Cancer Cause and Prevention Research program (CFDA 93.393) to test regulatory strategies promoting e-cigarette cessation among young adults. The University of Southern California will conduct a study using a simulated vape shop experimental laboratory space ("The Puff Point") to evaluate two innovative policy interventions designed to...
- The Department of Health and Human Services National Institutes of Health Office of the Director awarded the University of Louisville $782,293 on June 10, 2026, under the Family Smoking Prevention and Tobacco Control Act Regulatory Research program (CFDA 93.077, Project Grant R01HL185698). The University of Louisville's Office of Research & Innovation will conduct research examining how coolants such as menthol, WS-3, and WS-23 used in electronic cigarettes alter cardiorespiratory and...
- The Department of Health and Human Services National Institutes of Health Office of the Director awarded Health Research, Inc. Roswell Park Division (doing business as Health Research At Roswell Park) $867,448 under the Family Smoking Prevention and Tobacco Control Act Regulatory Research program (CFDA 93.077) on August 1, 2026. The recipient will conduct research assessing whether use of fruit-flavored electronic nicotine delivery systems (ENDS) relates to smoking reductions in people who smoke...
- The National Heart Lung and Blood Institute awarded $827,439 to Lundquist Institute For Biomedical Innovation At Harbor-UCLA Medical Center on September 1, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to investigate mechanisms by which perinatal nicotine vaping exposure dysregulates pulmonary group 2 innate lymphoid cells (ILC2s) and promotes allergic asthma development in offspring. The research employs electronic nicotine delivery system (ENDS) exposure models and...
- The National Heart, Lung, and Blood Institute awarded the University of Kansas Medical Center Research Institute $774,735 on September 1, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to investigate the effects of ethanol in e-liquids on nicotine delivery, toxicity, and immune response. The project examines how ethanol—present in commercially available e-liquids at concentrations ranging from 1 to 20 percent but not disclosed by manufacturers—alters e-liquid properties...
- The National Cancer Institute awarded the Board of Regents of the University of Nebraska, through its University of Nebraska Medical Center division, $948,630 under the Cancer Cause and Prevention Research program (CFDA 93.393) on August 1, 2026, for a naturalistic cohort study examining the real-world effectiveness of smoking cessation aids in US adults. The project will conduct a longitudinal survey study using the Understanding America Study, a nationally representative panel of 20,000 US...
The National Heart, Lung, and Blood Institute awarded the University of Maryland, Baltimore $116,625 under Project Grant R03HL188068 on August 15, 2026, to conduct a randomized, within-subject crossover study comparing cardiovascular effects of combustible cigarette smoking and electronic cigarette use in older adults with hypertension. The study enrolls 30 participants aged 50 and older with hypertension and assigns each to two 14-day phases: continued smoking and exclusive use of an authorized electronic cigarette product. Aim 1 evaluates laboratory-based cardiovascular health measures including resting blood pressure and heart rate across both conditions. Aim 2 assesses real-world cardiovascular function through remote measurements of blood pressure, heart rate, heart rate variability, and heart rate per step—a composite indicator of cardiovascular efficiency. The work addresses a high-priority research gap, as older adults bear the greatest burden of smoking-related cardiovascular disease yet remain significantly underrepresented in tobacco research and represent the only age group not experiencing a decline in smoking prevalence. The award funds research under the Family Smoking Prevention and Tobacco Control Act Regulatory Research program (CFDA 93.077), which supports regulatory research providing scientific evidence to guide implementation of tobacco product regulation. Performance occurs at the Baltimore campus in Baltimore, Maryland, with a period of performance extending through July 31, 2028.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $116.6k | 8/14/26 |