Maternal acetaminophen use and childhood cancer
Ended Project Grant Awarded Last action
- Award ID
- R03CA273608
- Recipient
-
University Of North Texas UEI G47WN1XZNWX9 Part of University Of North Texas
- Awarding agency
-
National Cancer Institute
National Institutes of Health, Department of Health and Human Services
- Obligated
- $376,066
Award facts
- Assistance listing
- 93.393 Cancer Cause and Prevention Research
- Completion date
- Originally
- Place of performance
- Texas, USA
Award details come from USAspending.gov.
Description
- Abstract
- Approximately 65% of US pregnant women take acetaminophen (in the US, branded as tylenol; in europe, paracetamol). Despite increasing concerns for its safety in pregnancy, with reported liver and developmental toxicity and risks for adverse child outcomes including hyperkinetic disorders and autism, IT remains widely used and continues to be endorsed by US physician groups and the US FDA. IT is well-established that pregnancy intake of medications can have carcinogenic impacts on offspring, as shown by diethylstilbestrol (DES) and vaginal adenocarcinoma. Yet potential carcinogenic impacts from acetaminophen are understudied. This study will be conducted via linkage of national health insurance claims databases in taiwan, including the taiwan maternal and child health database (which includes the pharmaceutical register and the birth registry, among other sources) and the cancer registry. Data on demographic, gestational, and other factors will be available from other national registers. The aims of this study are to investigate the role of acetaminophen in cancer risk, addressing needs voiced by regulatory agencies, for more thorough research to better understand the safety of acetaminophen in pregnancy and to inform regulatory recommendations.
Transactions
| Action | Obligated | Date |
|---|---|---|
| Amendment | -$41 | |
| Amendment | -$41 | |
| Amendment | -$77 | |
| Amendment | $0 | |
| Amendment | $0 | |
| Amendment | $31,045 | |
| Amendment | $31,045 | |
| Amendment | $57,988 | |
| Amendment | $57,988 | |
| Amendment | $57,988 | |
| Amendment | $70,086 | |
| Original award | $70,086 |
Show all 12
Subawards
| Subrecipient | Amount | Awarded |
|---|---|---|
| National Cheng Kung University | $86,802 |
Quick answers
Who received award R03CA273608?
R03CA273608 was awarded to University Of North Texas by National Cancer Institute (National Institutes of Health) on August 1, 2022.
How much is award R03CA273608 worth?
$376,066 has been obligated on R03CA273608.
On GovTribe
See this award's full record
- Every transaction and subaward
- The recipient's other awards and teaming partners
- Similar grant awards
- Ask GovTribe AI about this award