Project Grant R03AI199486
- Federal Grant Award Summary National Jewish Health received a $470,219 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded February 5, 2026, with a completion date of January 31, 2028. This award supports fundamental biomedical research investigating the role of resident memory T cells (TRM) in chronic lung disease and viral infections, specifically examining how these immune...
- Federal Project Grant Summary National Jewish Health received a $776,394 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded February 19, 2026, with completion scheduled for January 31, 2031. The award funds basic science research investigating the prenatal programming of immune cells—specifically mast cells—in the context of airway remodeling and asthma pathogenesis. The research...
- Federal Project Grant Award Summary Cincinnati Children's Hospital Medical Center received a $202,500 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded June 16, 2026, with a completion date of May 31, 2028. The grant funds research examining the role of peroxisomes and peroxisomal fatty acid beta-oxidation (PFABO) in regulating CD4+ T cell inflammatory responses and immune-related...
- Project Grant Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Regents of the University of Colorado–Denver a $763,102 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective May 22, 2026, with a completion date of April 30, 2031. The grant funds research to elucidate novel roles of mucosal tissue eosinophils in the dissemination of type 2 immunity and allergic disease progression. The project addresses a critical...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $234,000 to The Regents of the University of Colorado, doing business as University of Colorado-Denver, under the Allergy and Infectious Diseases Research program (CFDA 93.855) on April 23, 2026, with a completion date of March 31, 2028. This Project Grant funds research to dissect the transcriptional control of human mucosal-associated invariant T (MAIT) cells, a non-MHC-restricted...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $429,000 Project Grant to the University of Colorado-Denver under the Allergy and Infectious Diseases Research program (CFDA 93.855) on July 3, 2025, with a completion date of June 30, 2027. This research project delivers investigative services focused on understanding the pathogenic mechanisms of Type 1 Diabetes (T1D), specifically examining the role of pH levels in insulin-producing...
- Award Summary Oregon Health & Science University received a $442,758 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective February 9, 2026 through January 31, 2028. The project aims to identify drug targets in Mycobacterium abscessus (MAB) through the application of fluorescent probes to elucidate the mechanistic basis of dual beta-lactam antibiotic therapy. MAB causes...
- Federal Project Grant Award Summary Rockefeller University received a $667,659 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded June 1, 2026, with a completion date of May 31, 2031. The grant funds research to establish functional genomic mapping of gene vulnerabilities in Mycobacterium abscessus (MABS), an increasingly prevalent cause of chronic lung infections in patients...
- National Jewish Health received a $429,546 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) to evaluate antibiotic regimen efficacy for tuberculosis (TB) treatment. The award, effective August 8, 2025, through July 31, 2027, supports research utilizing SEARCH-TB, an RNA-sequencing platform designed to quantify drug-induced bacterial injury and physiological adaptations in Mycobacterium...
- Federal Grant Award Summary St. Jude Children's Research Hospital Inc. received a $3.43 million Project Grant from the National Institute of Allergy and Infectious Diseases under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective July 22, 2025, through June 30, 2029. The award supports fundamental biomedical research investigating epigenetic checkpoint regulation of naive T-cell quiescence and peripheral tolerance—specifically examining how the ascorbate transporter...
Grant Summary National Jewish Health received a $164,350 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective July 1, 2026 through June 30, 2027. The project, titled "Glucose and Glutamine Transport: Novel Targets in Cystic Fibrosis Immune Responses," investigates solute carrier proteins SLC2A4RG and SLC38A9 as potential therapeutic targets to reduce pulmonary inflammation in cystic fibrosis (CF) patients. The research builds on preliminary findings demonstrating that T cell metabolic reprogramming occurs in adults with CF receiving CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) modulator therapy, particularly triple combination therapy with elexacaftor-tezacaftor-ivacaftor (ETI). The deliverables include gene-editing studies, bioenergetic analyses, and translational research utilizing clinically relevant patient samples to elucidate the roles of these nutrient transporters in baseline health and disease states. The project aims to identify mechanisms by which glucose and amino acid transport regulation—driven by master metabolic regulators such as mTOR—can be leveraged to further reduce CF-related inflammation and improve patient outcomes, particularly for individuals who continue experiencing pulmonary exacerbations despite current CFTR modulator therapy or remain ineligible for such treatment based on genotype.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $164.4k | 7/1/26 |