Project Grant R01TS000346
- This federal Cooperative Agreement award, titled "SPECTRAL FLOW CYTOMETRY IDENTIFIES NEW IMMUNE SIGNATURES THAT PROVIDE PERSONALIZED ALS RISK AND PROGRESSION BIOMARKERS AND THERAPEUTIC TARGETS", is funded by the Agency for Toxic Substances and Disease Registry (ATSDR) under the State Capacity Building Program (CFDA 93.240). The $500,000.00 award, effective September 30, 2025, supports research conducted by the Regents of the University of Michigan to identify new biomarkers and...
- The Defense Health Agency awarded a $929,948 Project Grant to The Washington University in St. Louis, Missouri to support the research project "TARGETING TDP-43 MITOCHONDRIAL MISLOCALIZATION IN ALS". This grant is funded through the Military Medical Research and Development program (CFDA 12.420), which supports biomedical research aimed at improving the health and care of military service members, veterans, and their families. The research project will investigate mitochondrial...
- This federal Project Grant award of $836,992.00, provided by the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420), supports research to investigate the effects of military-associated environmental toxins on motor neurons and glial cells in sporadic amyotrophic lateral sclerosis (ALS) at the University of Massachusetts Medical School (UMMS) in Worcester, MA. The research aims to transform healthcare for military service members, veterans, and the...
- The Project Grant award of $3,133,754 from the National Institute of Environmental Health Sciences (NIEHS, CFDA 93.113 Environmental Health) aims to comprehensively assess the exposome (a person's cumulative lifetime exposures) and epigenome in a Michigan cohort to determine how they associate with amyotrophic lateral sclerosis (ALS) risk and survival. The research, conducted by the Regents of the University of Michigan, seeks to gain insight into ALS disease etiology by examining the...
- The National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health Federal Grant Program (CFDA 93.113), awarded a $484,122 Project Grant to Black Hills State University (BHSU) on August 20, 2025. The grant supports research to elucidate the mechanisms of beta-methylamino-L-alanine (BMAA) neurotoxin-induced toxicity and to develop and test novel aptamer inhibitors of BMAA's activity in human cell lines. The research aims to provide mechanistic insights into the...
- This federal Project Grant award, valued at $1,103,084.00, was issued by the Defense Health Agency under the Military Medical Research and Development (CFDA 12.420) program. The funding supports the development of a personalized blood-based diagnostic assay for early detection of Amyotrophic Lateral Sclerosis (ALS) at Arizona State University. The university will collaborate with a sub-awardee, Georgetown University, to conduct the research. The project aims to transform healthcare for...
- The federal Project Grant award, valued at $250,000.00, was provided by the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) to The Washington University's Office of Sponsored Research Services Division. The award will fund a study on the "SUBCLINICAL PATHOPHYSIOLOGY OF MOTOR PROCESSING IN PEOPLE WITH MULTIPLE SCLEROSIS" over a 2-year period from September 30, 2024 to September 29, 2026. As a prominent private research university, The...
- This $847,643 federal Project Grant was awarded on April 15, 2025 by the U.S. Department of Energy's Office of Science Financial Assistance Program (CFDA 81.049) to The Washington University in University City, Missouri. The grant supports research on new particle formation, subsequent particle growth, and their contribution to cloud condensation nuclei population in the Southeast U.S. The funded project aims to advance scientific understanding of complex physical, biological, and...
- This federal Project Grant award of $320,000.00 from the Department of the Army Medical Command's Military Medical Research and Development program (CFDA 12.420) supports a research project titled "MULTIPLE SCLEROSIS DISPARITIES: EVALUATION OF CHRONIC STRESS LOAD AND SOCIAL FACTORS". The award, effective September 30, 2024 through September 29, 2026, has been transferred from Johns Hopkins University to The Washington University in St. Louis. The project aims to advance research on...
- This Project Grant award, provided by the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420), supports research to develop neuronal exosome-based biomarkers for the diagnosis and disease progression of amyotrophic lateral sclerosis (ALS). The total award amount is $1,181,251.00, with a performance period from April 15, 2025 to April 14, 2028. The principal investigator for this grant is the University of California, Los Angeles (UCLA), which has a...
This federal Project Grant award of $299,928.00 was provided by the Agency for Toxic Substances and Disease Registry (ATSDR), under the State Capacity Building program (CFDA 93.240), to the Washington University in Missouri. The objective of this 3-year award, with a period of performance from September 30, 2025 to September 29, 2028, is to conduct research on the relationship between multiple air pollutants and amyotrophic lateral sclerosis (ALS). As a leading academic research institution, the Washington University has extensive expertise in executing specialized research projects for various federal agencies, including biomedical sciences, environmental studies, and clinical research. This grant will support the university's efforts to evaluate exposure pathways, educate communities on environmental health risks, and develop strategies to prevent harmful exposures related to air pollution and its potential links to ALS.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $299.9k | 9/24/25 |