Project Grant R01MH141161
- The National Institute of Mental Health awarded the University of Illinois $440,908 on July 27, 2026, under the Mental Health Research Grants program (CFDA 93.242) to support a project investigating the roles of the prefrontal cortex and ventral hippocampus during adolescence in the maturation of social and cognitive behaviors. The research examines how changes in GABAergic inhibitory transmission in these limbic structures contribute to the refinement of higher cognitive functions and social...
- The National Institute of Mental Health awarded Children's Research Institute $654,005 on June 1, 2026, under the Mental Health Research Grants program (CFDA 93.242) to investigate the function of paralaminar amygdala neurons from adolescence to adulthood using a mouse model. The recipient will examine how paralaminar nucleus neuronal responses change over the adolescent-to-early-adulthood transition, determine the necessity and sufficiency of these neurons in that transition, and characterize...
- The National Institute of Mental Health awarded Northeastern University $157,500 on September 1, 2026, under the Mental Health Research Grants program (CFDA 93.242) to explore the role of microglia in developmental effects of early life adversity on prefrontal cortex glutamate receptor development. The research investigates how microglia, resident immune cells of the brain, drive changes in NMDA receptor expression in adolescents exposed to early life adversity such as maternal separation. Prior...
- The National Institute of Mental Health awarded the University of North Carolina at Chapel Hill $572,294 on August 1, 2026, under the Mental Health Research Grants program (CFDA 93.242) to investigate the effects of adolescent social isolation on glial dysfunction and social behavior in adulthood. The award supports a three-year research project running through July 31, 2029, performed in Chapel Hill, North Carolina. The research tests the hypothesis that adolescent social isolation stress...
- The National Institute of Mental Health awarded Massachusetts Institute of Technology $735,182 under the Mental Health Research Grants program (CFDA 93.242) on August 1, 2026, to investigate how social interactions promote recovery from viral infections through interleukin-10 (IL-10)–mediated mechanisms. The research uses murine models to explore the neural-immune pathways linking social touch, oxytocin, and IL-10 in recovery from virally induced sickness behaviors. The project will determine...
- The National Institute of Mental Health awarded $1.579 million to the Research Foundation For Mental Hygiene, Inc., operating as the New York State Psychiatric Institute, on July 1, 2026, under the Mental Health Research Grants program (CFDA 93.242) to fund basic neuroscience research into the circuit mechanisms by which early-life adversity produces sustained reward deficits. The research examines how childhood trauma—including abuse, neglect, and chronic stress—alters neural circuits governing...
- The National Institute of Mental Health awarded Massachusetts Institute of Technology $127,224 under the Mental Health Research Grants program (CFDA 93.242) on August 1, 2026, to investigate neural mechanisms governing sensory-driven decision making through study of amygdala-striatal pathways. The K99 award (K99MH141244) funds research into how basolateral amygdala neurons projecting to the tail of the striatum instruct the selection of instrumental actions during perceptual decision making. The...
- The National Institute of Mental Health awarded the University of Massachusetts Medical School $474,500 on August 1, 2026, under the Mental Health Research Grants program (CFDA 93.242) to investigate the relationship between puberty, interoceptive neural networks, and anxiety symptoms in adolescents. The research employs functional magnetic resonance imaging to characterize how pubertal changes to cortical body representation in primary somatosensory and insular cortices relate to...
- The National Institute of Mental Health awarded Scripps Research Institute $878,601 on April 1, 2026, under the Mental Health Research Grants program (CFDA 93.242) to support structural remodeling of neural circuits via multisynaptic boutons. The research uses three-dimensional electron microscopy at nanometer resolution to reconstruct neuronal connectomes, individual synapses, and glia in the mammalian brain. The work combines 3D-EM with chemogenetic techniques for labeling cellular ensembles...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded a $433,125 Project Grant to the University of California, Los Angeles under the Mental Health Research Grants program (CFDA 93.242) for a two-year project period from September 18, 2025 to September 17, 2027. This research initiative investigates the asymmetrical development of early B cell factor gene 1 (EBF1)-positive cells in the central amygdala and their functional consequences in emotion regulation and...
The National Institute of Mental Health awarded Rosalind Franklin University of Medicine & Science $465,301 on July 25, 2026, under the Mental Health Research Grants program (CFDA 93.242) to investigate how social deprivation during adolescence impairs basomedial amygdala development and compromises social behavior. The research examines the role of the basomedial amygdala in regulating social engagement across developmental stages, with specific focus on how atypical social experiences—including social isolation and deprivation—alter inhibitory gabaergic tone and infralimbic cortical inputs that normally mature during adolescence. The project addresses vulnerabilities to social perturbations that emerged during the COVID-19 pandemic, using animal models to identify how developmental disruptions in amygdala circuitry contribute to impaired social behaviors. The award covers the period July 25, 2026, through April 30, 2031, with place of performance in North Chicago, Illinois. Project Grants under this program support specified project periods not in excess of five years and are evaluated on scientific and technical merit, program relevance, and program balance through NIH peer review.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $465.3k | 7/23/26 |