The Washington University Office of Sponsored Research Services has been awarded a 4-year, $665,225 Project Grant (R01MH139471) from the National Institute of Mental Health's Mental Health Research Grants program (CFDA 93.242). The grant will fund the "SUUBI4PREP: Improving PrEP Access and Adherence among Adolescent Girls and Young Women in Uganda" project. The goal is to develop and evaluate a multilevel intervention combining HIV risk reduction counseling, peer support for PrEP access and adherence, and economic empowerment components to address barriers to PrEP uptake among adolescent girls and young women in Uganda. The study will randomly assign 600 participants across three arms to examine the impacts on PrEP initiation, adherence, and associated mechanisms. The project aims to provide evidence for effective, scalable approaches to improving PrEP access and utilization to reduce HIV incidence in this high-risk population.