Project Grant R01MH137331
Award Date
7/1/25
Completion Date
4/30/30
Dollars Obligated
$514K
Federal Agency
National Institute of Mental Health
Federal Grant Program
93.242
Assistance Type
Project Grant
Place of Performance
Oklahoma City, OK, USA
Similar Awards
The National Institute of Mental Health (NIMH) awarded a $215,343 Project Grant (CFDA 93.242 - Mental Health Research Grants) to the Laureate Institute for Brain Research, LLC in Tulsa, Oklahoma. The funding will support a study to determine the dose-dependent effects of low-intensity focused ultrasound (LIFU) applied to white matter tracts connecting the thalamus with the subgenual cingulate and orbitofrontal cortices. Specifically, the study aims to 1) define the relationship between LIFU dose...
This federal Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), is focused on elucidating the reward network modulation effects of deep brain stimulation (DBS) of the medial forebrain bundle (MFB) for treatment-resistant depression (TRD). The $638,872 award aims to characterize the temporality of reward network changes induced by MFB DBS using functional and metabolic brain imaging, as well as confirm the...
This federal Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) provides $781,464 to develop a "causal wiring diagram of transdiagnostic brain functions." The research aims to use brain stimulation technology and functional MRI to map causal brain circuitry associated with a range of mental health conditions, including major depression, obsessive-compulsive disorder, schizophrenia, and generalized...
This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), is focused on developing a novel, non-invasive strategy to degrade perineuronal nets (PNNs) in the brain as a potential treatment for excessive, repetitive behavior associated with neuropsychiatric disorders. The $282,625 award, effective April 1, 2025 through March 31, 2026, will support research at the University of Virginia to optimize the use of...
This federal Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) provides $2,694,945 to the Lieber Institute for Brain Development (LIBD) to conduct research on understanding the cellular and circuit mechanisms underlying schizophrenia. The key products and services to be delivered under this award include: 1) Replicating and expanding on prior findings from 2D cell culture models of patient-derived induced...
This Project Grant award, funded by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants (CFDA 93.242) program, aims to improve the understanding and treatment of depression. The $784,096 award to The Leland Stanford Junior University will develop optimized methods for measuring brain excitability in depression using repetitive transcranial magnetic stimulation (rTMS). Specifically, the project will: 1) investigate how adjusting rTMS parameters affects neural...
This $449,228 Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) supports the development of an integrated system for long-term electrophysiological profiling of human brain organoids. The key products and services to be delivered include: A biological assay chamber that supports chronic electrophysiology while maintaining the health of brain organoids. High-fidelity, 3D neural probes for chronic, extracellular...
The federal Project Grant award of $176,979.00 was provided by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242). The award aims to develop personalized neuromodulation interventions that can effectively target and reduce social avoidance behavior (SAB) in patients with major depressive disorder (MDD) or social anxiety disorder (SAD). Specifically, the research will use transcranial magnetic stimulation (TMS) to causally modulate...
This federal Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) aims to advance transcranial magnetic stimulation (TMS) technologies for the treatment of psychiatric disorders. The $382,480 award, granted on September 26, 2024, will support research to validate a closed-loop approach for prefrontal TMS using real-time electroencephalographic (EEG) recordings in a non-human primate model. The key objectives are...
This federal Project Grant award of $968,769 from the National Institute of Mental Health (NIMH) under CFDA 93.242 Mental Health Research Grants will fund a study to investigate the efficacy of maintenance repetitive transcranial magnetic stimulation (rTMS) for individuals with treatment-resistant depression. The study will recruit 75 participants across three sites - the University of California San Diego, Cornell University, and Australian National University - into a double-blind, three-arm...