TU'washindi: a relationship-focused intervention to reduce GBV and increase prep uptake and adherence among kenyan agyw
Active Project Grant Awarded Last action
- Award ID
- R01MH125671
- Recipient
-
Research Triangle Institute UEI JJHCMK4NT5N3
- Awarding agency
-
National Institute of Mental Health
National Institutes of Health, Department of Health and Human Services
- Obligated
- $6,113,901
Award facts
- Assistance listing
- 93.242 Mental Health Research Grants
- Completion date 87% complete
- Originally
- Place of performance
- Durham, NC 27713, USA
Award details come from USAspending.gov.
Description
- Abstract
- This R01 application, led by an early stage investigator, aims to test the effectiveness of a multilevel community- based intervention to increase uptake and adherence to oral pre-exposure prophylaxis (PREP) among adolescent girls and young women (AGYW) in kenya. AGYW in this setting live in a context of heightened gender inequality and risk of intimate partner violence (IPV) and represent a large subpopulation who are uniquely vulnerable to HIV infection. In addition to having higher HIV incidence, women experiencing IPV are less likely to initiate and persist with PREP, limiting the protective benefit of this efficacious biomedical prevention intervention. Barriers to PREP uptake and adherence occur at multiple levels of the socioecological model, including low individual self-efficacy, partner opposition, and community stigma. TU'washindi NA PREP (we are winners with PREP) is a multi-level, community-based intervention designed specifically to address these challenges among AGYW in siaya county, kenya. Designed by our team using participatory methods engaging local AGYW (R34 MH114519), the intervention includes three components delivered over 6 months: an eight-session, empowerment-based support club for AGYW, community sensitization targeted toward male partners, and PREP education events for couples. Activities are designed to be integrated into youth-focused programming to ensure efficiency and sustainability. Results from a pilot cluster- randomized controlled trial conducted with 100 AGYW at six sites indicate high feasibility and acceptability, and preliminary effectiveness: intervention arm participants had 2-fold higher PREP uptake and adherence (P
Transactions
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| Amendment | $909,729 | |
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| Amendment | $670,476 | |
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| Amendment | $651,257 | |
| Amendment | $656,636 | |
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| Original award | $0 |
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Subawards
| Subrecipient | Amount | Awarded |
|---|---|---|
| Impact Research And Development Organisation | $25,819 | |
| University Of Washington | $41,629 | |
| Impact Research And Development Organisation | $332,677 |
Quick answers
Who received award R01MH125671?
R01MH125671 was awarded to Research Triangle Institute by National Institute of Mental Health (National Institutes of Health) on August 19, 2021.
How much is award R01MH125671 worth?
$6,113,901 has been obligated on R01MH125671.
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