This $2,963,428 Project Grant award from the National Science Foundation's Biological Sciences program (CFDA 47.074) aims to develop critical infrastructure and tools for interpreting genomic data. The project will create high-quality genome assembly workflows, comprehensive documentation, and interactive training materials to make these advanced genomic analysis capabilities accessible to a wide audience of biology researchers. This will enable downstream discoveries in areas such as...
The federal Project Grant award R01LM014698, funded by the National Institute of Environmental Health Sciences (NIEHS) under the Medical Library Assistance (CFDA 93.879) program, aims to develop a better understanding of how data errors impact bioinformatics software and algorithms. The $608,586 award, which runs from January 1, 2025 to December 31, 2028, will support research at the University of Maryland, College Park to assess and improve the resilience of bioinformatics pipelines to data...
This $794,457 federal Project Grant award from the National Science Foundation's (NSF) Biological Sciences program (CFDA 47.074) will support the development of new genetic analysis tools. The goal is to incorporate molecular and cellular biology knowledge, such as gene expression patterns and regulatory networks, directly into statistical models used to map genes, predict traits, and simulate changes in the genotype-to-phenotype relationships. The research will be conducted using simulated...
This Project Grant award R01LM014593 for $997,678.00, funded by the National Institute of Environmental Health Sciences (NIEHS) under the Medical Library Assistance (CFDA 93.879) program, aims to develop automated methods for standardizing and enhancing the metadata in large biomedical databases such as the Sequence Read Archive (SRA) and Gene Expression Omnibus (GEO). The proposed methods will use machine learning and natural language processing approaches to assign standardized ontology...
This Project Grant award from the National Science Foundation (NSF) Biological Sciences (CFDA 47.074) program aims to develop advanced computational tools and methods for analyzing genetic diversity in plants, particularly as a means to understand and address the impacts of climate change. With total funding of $1,346,558 over a 4-year period from October 2024 to September 2028, the project will be conducted by the National Center for Genome Resources (NCGR), a non-profit research institute in...
This Project Grant award from the National Human Genome Research Institute (CFDA 93.172 - Human Genome Research) provides $339,000.00 to Rockefeller University to develop and expand the GFASTAR software ecosystem, a suite of algorithms and tools for evaluating and manipulating genome assembly graphs. The goal is to advance capabilities for generating high-quality, telomere-to-telomere (T2T) reference genomes at scale across multiple species. The key products and services to be delivered include:...
This Project Grant award of $579,698 from the National Human Genome Research Institute (NHGRI), part of the Human Genome Research federal grant program (CFDA 93.172), supports the development of the "FACETING GEMS (Genomic Education Modules) for the Entry-Level Workforce" program. The key products and services to be delivered under this award include: (1) providing accessible, research-focused genomics training modules; (2) training and motivating partner site faculty; (3) fostering...
This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) provides $177,901 to South Dakota State University to develop a user-friendly, interactive, and reproducible bioinformatics tool called ShinyGO for conducting gene enrichment analysis. The goal is to enhance ShinyGO's functionality, improve its reproducibility, and expand its comprehensive database covering over 14,000 organisms. This...
The federal Project Grant award from the National Institutes of Health (NIH) Office of the Director under the Trans-NIH Research Support program (CFDA 93.310) provides $1,507,500 to the University of Massachusetts Medical School (UMass Medical) to expand the capabilities of third-generation DNA/RNA sequencing technologies. The project aims to generate rapid and cost-effective training libraries to allow for direct detection of common DNA damage and RNA modifications, enabling innovative...
This Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) provides $248,893 to Northeastern University to develop a data-driven approach to automatically identify biomedical tools and methods, collectively referred to as BioTools, and to quantify their impact across multiple dimensions. The key objectives are to: 1) Create a ground-truth corpus by extracting laboratory techniques, software...