Project Grant R01HL188828
- The National Institute of Dental and Craniofacial Research awarded the Regents of the University of Michigan $429,000 on June 5, 2026, under the Oral Diseases and Disorders Research program (CFDA 93.121) to investigate the effects of recurrent periodontitis on hematopoietic stem cell function. The research establishes a chronic periodontitis model to examine long-term effects on hematopoietic stem cells and defines the functional consequences of chronic periodontitis on these cells, accounting...
- The National Institute of Dental and Craniofacial Research awarded the Regents of the University of Michigan $710,519 on August 1, 2026, under the Oral Diseases and Disorders Research program (CFDA 93.121) to establish a comprehensive, web-based developmental monitoring system for infants and toddlers with orofacial clefts. The project will track developmental status and trajectories across multiple domains—social/communication/cognition skills, motor abilities, early relational health, sleep,...
- The National Heart, Lung, and Blood Institute awarded the Regents of the University of Michigan $191,629 on May 15, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to investigate venous thromboembolism risk and prevention strategies in pregnant and postpartum patients with sickle cell disease. The funded research comprises three aims: building a data repository of pregnant and postpartum patients with sickle cell disease to determine venous thromboembolism and bleeding...
- The National Heart, Lung, and Blood Institute awarded Vanderbilt University Medical Center $873,449 on August 15, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to evaluate modern pharmacotherapy treatment regimens and prophylaxis for reducing infections in sickle cell disease. The recipient will conduct a population-based retrospective cohort study leveraging the Sickle Cell Data Collection Network (2010–2024) to assess children with sickle cell disease in Georgia,...
- The National Institute of Dental and Craniofacial Research awarded the University of Alabama at Birmingham $666,812 under the Oral Diseases and Disorders Research program (CFDA 93.121) on July 14, 2026, for a multilevel retrospective cohort study examining the impacts of Medicaid dental benefits expansion on oral healthcare workforce composition and services delivery at federally qualified health centers. The research employs an event-study difference-in-differences design using Uniform Data...
- The National Heart, Lung, and Blood Institute awarded Duke University $238,516 on August 1, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to conduct admixture mapping of genetic modifiers in sickle cell disease. The research leverages the National Heart, Lung, and Blood Institute's TOPMed program, which includes multiple cross-sectional adult sickle cell disease cohorts totaling more than 4,000 participants with whole genome sequencing data and extensive clinical...
- The National Institute of Dental and Craniofacial Research, an operating division of the Department of Health and Human Services National Institutes of Health, awarded Regents of the University of Michigan $600,214 on August 1, 2026, under the Oral Diseases and Disorders Research program (CFDA 93.121) to define the neuronal basis of odontogenic pain and identify targets for non-opioid analgesic development. The project, led by Dr. Joshua Emrick, investigates the cells, circuits, and behavioral...
- The National Institute of Dental and Craniofacial Research, a component of the Department of Health and Human Services National Institutes of Health, awarded $527,732 to the Regents of the University of Michigan on February 15, 2026, under the Oral Diseases and Disorders Research program (CFDA 93.121) to investigate the role of tissue homeostasis in Sjögren's disease. The research examines how abnormal cholesterol and lipid metabolism in salivary glands contributes to the development of...
- The National Institute of Dental and Craniofacial Research awarded Michigan State University (operating as Henry Ford Health+Michigan State University Health Sciences) $726,442 under the Oral Diseases and Disorders Research program (CFDA 93.121) on September 19, 2025, for a Project Grant (R56DE035224). The research investigates X-chromosomal dysregulation in primary Sjögren's disease, a female-predominant autoimmune condition. The project examines the molecular mechanism by which MIR6891-5P,...
- The National Institute of Dental and Craniofacial Research awarded $593,876 to the Regents of the University of Michigan on August 7, 2026, under the Oral Diseases and Disorders Research program (CFDA 93.121) to investigate the molecular mechanisms regulating peritubular dentin mineralization and develop bioengineered strategies for targeted dentin reconstruction. The research uses six mouse models with varied amounts of dentin sialoprotein (DSP), dentin phosphoprotein (DPP), and chondroitin...
The National Heart, Lung, and Blood Institute awarded the Regents of the University of Michigan $920,152 on September 1, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to conduct a study examining the access, timing, and impact of dental care on health outcomes in children with sickle cell disease. The research uses national Medicaid data to determine whether preventive dental care improves outcomes for children with sickle cell disease and whether some children would benefit from additional dental visits to monitor oral health and detect problems early. Aim 1 examines receipt of preventive and other types of dental care among children with sickle cell disease and assesses associations with receipt of care by individual-level factors such as demographics and patterns of healthcare use, community-level factors such as rurality and dentist supply, and state-level factors such as Medicaid payment for dental care and dentist participation in Medicaid. Aim 2 estimates the impact of receipt of preventive dental care on long-term sickle cell disease-related adverse events, including total acute care utilization, pain crises, stroke, and infection, using an instrumental variables estimation approach to address potential selection bias. The award covers the period of performance from September 1, 2026, through May 31, 2030, with place of performance in Ann Arbor, Michigan. This is a project grant, the standard assistance type for investigator-initiated research at NIH.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $920.2k | 8/13/26 |