Project Grant R01GM169398
- The National Institute of General Medical Sciences (NIGMS) awarded the University of Arizona $410,775 on July 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to advance synthetic bacterial adhesion tools and engineer multicellular bacterial consortia for health-relevant applications. The research focuses on developing novel synthetic cell-cell adhesion features through protein engineering, creating new synthetic genetic circuits that enable controlled...
- The National Institute of General Medical Sciences awarded Arizona State University $2,081,661 on August 10, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop plasmonic and evanescent scattering microscopy technologies for label-free functional imaging of single molecular and cellular activities. The recipient will advance optical detection methods that measure intrinsic molecular and cellular optical properties without fluorescent or radioactive...
- The National Institute of General Medical Sciences, an operating division of the Department of Health and Human Services National Institutes of Health, awarded Arizona State University $404,180 on July 13, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to investigate how bacterial predation via the type VI secretion system shapes ecological and evolutionary dynamics in microbial communities. The D'Souza Lab will study T6SS-mediated antagonism in two bacterial...
- Federal Project Grant Award Summary Arizona State University received a $700,000 Project Grant from the National Science Foundation (NSF) Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074), effective August 1, 2025, through July 31, 2028. The award funds research to elucidate and understand "covert" or non-obligate metabolic interactions within synthetic microbial communities—interactions that are not essential to community survival but...
- The National Institute of General Medical Sciences awarded Arizona State University $363,365 on July 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to advance spin-based quantum sensors for single-cell analysis. The research will develop optically addressable spin-qubit magnetometers to detect biological magnetic fields at the nanoscale, focusing on improving sensor coherence and biocompatibility to enable label-free detection of cellular activities...
- The National Science Foundation Division of Molecular and Cellular Biosciences awarded Arizona State University $799,995 on August 1, 2026, under the Biological Sciences program (CFDA 47.074) to establish a quantitative framework for understanding reciprocal interactions between biomolecular condensates and cellular growth. The project will use integrated experimental and computational approaches to determine how cellular growth regulates condensate formation, dissolution, and phase-separation...
- The National Institute of General Medical Sciences awarded Arizona State University $378,995 on September 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to decode the toxicity-efficacy paradox in gene and nucleic acid therapies. Over five years through August 31, 2031, the funded research will generate an integrated atlas of escape-induced toxicities using phosphoproteomics, transcriptomics, and mediator profiling to map how endosomal escape location and...
- Federal Project Grant Award Summary Arizona State University received a $413,036 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective September 1, 2025, through August 31, 2027. The award supports the development of a novel single-molecule glycosaminoglycan (GAG) sequencing method using fluorophore-labeled lysosomal enzymes. Glycosaminoglycans are large, linear, sulfated...
- The National Institute of General Medical Sciences awarded Texas State University $401,250 on August 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to study the mechanisms of intergenomic epistasis and environmental context in animal-microbe symbioses. Over the five-year performance period through April 30, 2031, the research will use the Aiptasia anemone and its photosynthetic algal symbiont as a model system to characterize how host and symbiont genotypes...
- Federal Project Grant Award Summary Arizona State University received a $1,977,264 Project Grant award, effective September 15, 2025, through August 31, 2029, under the National Institute of General Medical Sciences' Biomedical Research and Research Training program (CFDA 93.859). The award funds development of a novel multimodal imaging platform that integrates fluorescence super-resolution and tomographic polarized light imaging technologies to enable cellular and unicellular organism...
The National Institute of General Medical Sciences awarded Arizona State University $300,000 on August 10, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to investigate synthetic microbial communities and their ecosystem dynamics. The project develops and characterizes synthetic two-component and higher-order E. coli microbial communities with diverse inter-strain interaction topologies, coupling bacterial toxin-antitoxin systems with quorum sensing to create controllable experimental systems. Work focuses on three specific objectives: designing and validating synthetic communities with diverse interaction topologies through modeling and experimental construction; characterizing population dynamics rules in well-mixed liquid culture through perturbation data and model analysis; and mechanistically characterizing spatial patterning rules on solid surfaces. By engineering microbial strains with nearly identical genetic and physiological backgrounds, observed population dynamics will result primarily from inter-strain interactions, resource availability, and physical space limitations, enabling predictive mechanistic mathematical modeling of system behavior. Performance occurs in Tempe, Arizona, with a period of performance through May 31, 2030. The award is assistance type Project Grant. This is an R01 investigator-initiated basic research award supporting the NIGMS mission to advance understanding of biological processes foundational to disease diagnosis, treatment, and prevention.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $300.0k | 8/7/26 |