Project Grant R01GM169341
- The National Institute of General Medical Sciences awarded Oklahoma State University $373,960 on September 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to support research on genome evolution and design in small, single-stranded DNA phages (Microviridae). The award is structured as a Project Grant with a period of performance running through August 31, 2031. Work is performed in Oklahoma City, Oklahoma. The National Institute of General Medical Sciences...
- The National Institute of General Medical Sciences awarded the University of Oklahoma a Project Grant of $360,157 on September 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop and apply sulfenylcarbenes and sulfenylnitrenes as reagents for site-selective chemical transformations in drug discovery. The research addresses the slowdown in pharmaceutical development by expanding chemical space through scaffold hopping—transforming established drug...
- The National Institute of Environmental Health Sciences awarded Oklahoma State University $350,000 on August 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to investigate the bioavailability and toxicity of microplastic and cadmium mixtures in the human gastrointestinal system and to develop undergraduate research training in interdisciplinary environmental science. The project examines how environmental weathering and digestive processes affect the sorption...
- Federal Project Grant Award Summary The University of Oklahoma Health Sciences Center received a $700,000 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective September 1, 2025, through August 31, 2027. This award funds a two-year investigator-initiated research project focused on elucidating the molecular, cellular, and organism-level mechanisms by which endothelial tetraspanins inhibit...
- The National Center for Complementary and Integrative Health, part of the Department of Health and Human Services National Institutes of Health, awarded $413,972 to Oklahoma State University Center for Health Sciences on August 12, 2026, under the Research and Training in Complementary and Integrative Health program (CFDA 93.213). The award funds investigation of how early life stress triggers imbalances in gut bacterial genera, particularly Roseburia, and influences brain responses through...
- The National Science Foundation Office of Advanced Cyberinfrastructure awarded Oklahoma State University Center for Health Sciences $279,504 on October 1, 2026, to develop and deliver a cloud-enabled computational training program in biomedical evidence evaluation and meta-research methodology. Over 24 months through September 30, 2028, the recipient will operate at its Tulsa, Oklahoma facility to train two summer cohorts of approximately 15 students each in an intensive 8-week program...
- The National Institute of General Medical Sciences awarded The Ohio State University $383,169 on July 23, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop AI-powered computational models for translational research that benchmark the fidelity of animal models and organoid systems against human references and construct ensemble virtual cells to predict human cellular responses under perturbations. The award funds two integrated research directions....
- The National Institute of General Medical Sciences awarded Oregon State University $1.2 million on September 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to investigate novel regulatory mechanisms that control secondary metabolite biosynthesis in microorganisms. The funded research addresses the challenge of discovering and expressing biosynthetic gene clusters (BGCs) that produce bioactive natural products for drug development. The project tests two primary...
- The Department of Health and Human Services National Institutes of Health Office of the Director awarded Oklahoma Medical Research Foundation $805,745 on July 1, 2026, under the Research Infrastructure Programs (CFDA 93.351) to develop precision genome editing tools for functional characterization of genetic variants. The award funds development of a high-throughput, cost-effective platform for in vivo functional validation of human disease-associated genetic variants using zebrafish as a...
- The National Institute of General Medical Sciences (NIGMS), part of the National Institutes of Health and the Department of Health and Human Services, awarded $382,339 to the University of Oklahoma Health Sciences Center on July 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to support research on the regulation of hepatic drug transport proteins and identification of novel drug interaction signals. The research program focuses on understanding molecular...
The National Institute of General Medical Sciences awarded Oklahoma State University Center for Health Sciences $219,557 on August 14, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop and validate metrics for assessing the integrity and rhetorical framing of adverse event reporting in biomedical research. The project will create two novel indices: the Harms Reporting Integrity Index, measuring completeness, concordance, transparency, and timeliness of adverse event disclosures across trial registries and publications, and the Framing Risk Index, capturing rhetorical strategies that minimize reported harms. The recipient will link these indices to downstream regulatory and scientific outcomes—FDA labeling changes, guideline incorporation, citation dynamics, and workforce trajectories—using causal inference methods. The project will pilot pragmatic editorial interventions including discrepancy flagging tools, harms checklists, and framing prompts to improve reporting practices. Work is performed in Tulsa, Oklahoma, with a period of performance through April 30, 2030. The investigative team includes expertise in meta-research, machine learning and natural language processing, causal modeling, and clinical specialties, supported by preliminary data from 16 registry-publication concordance studies and qualitative analyses of framing practices.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $219.6k | 8/13/26 |