Development of single cell printing-liquid vortex capture-mass spectrometry for the metabolic profiling of single cells
Ended Project Grant Awarded Last action
- Award ID
- R01GM144421
- Recipient
-
Ut-Battelle LLC UEI ZLHJJ57QA2H8
- Awarding agency
-
National Institute of General Medical Sciences
National Institutes of Health, Department of Health and Human Services
- Obligated
- $759,691
Award facts
- Assistance listing
- 93.859 Biomedical Research and Research Training
- Completion date
- Place of performance
- Tennessee, USA
Award details come from USAspending.gov.
Description
- Abstract
- The mechanisms underpinning heterogeneous metabolic response between individual cells remain poorly understood, though such mechanisms have ramifications across nearly all of medicine, e.g., disease detection, response to stress, treatment, and more. Intracellular small molecule metabolite, lipid and therapeutic concentrations are often inferred through protein expression or directly measured as the average of 1000's of cells at once, providing only a population-level view of heterogeneous metabolic response. This obfuscates differentiation of anomalous metabolic cell phenotypes and small molecule associations occurring within cells. Currently there exists a GAP in analytical technologies for the measure of small molecules (
Transactions
| Action | Obligated | Date |
|---|---|---|
| Amendment | -$371,998 | |
| Amendment | -$749,328 | |
| Amendment | $377,330 | |
| Amendment | $380,058 | |
| Amendment | $0 | |
| Amendment | $0 | |
| Amendment | $0 | |
| Amendment | $374,543 | |
| Amendment | $374,543 | |
| Original award | $374,543 |
Quick answers
Who received award R01GM144421?
R01GM144421 was awarded to Ut-Battelle LLC by National Institute of General Medical Sciences (National Institutes of Health) on September 24, 2022.
How much is award R01GM144421 worth?
$759,691 has been obligated on R01GM144421.
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