Early life household air pollution, metal composition and cardiovascular health: evidence from graphs

Active Project Grant Awarded Last action

Award ID
R01ES034433
Recipient
Awarding agency
Obligated
$5,885,894

Award facts

Assistance listing
93.113 Environmental Health
Completion date 86% complete
Place of performance
New York, NY 10029, USA

Award details come from USAspending.gov.

Description

As the agency reported it.

Abstract
In low- and middle-income countries ~2.8 billion people are exposed daily to smoke from cooking fires, termed household air pollution (HAP), resulting in an estimated 2.3M deaths and 91.4M dalys in 2019. The largest proportion of HAP-attributable deaths are due to cardiovascular disease. Establishment of cardiovascular health in childhood is critical to reduce risk for future cardiovascular disease. We hypothesize that early life (prenatal to age 1) exposure to HAP alters cardiovascular development and programs future disease risk. We further hypothesize that the metal composition of air pollution drives toxicity. We propose to build on an existing pregnancy cohort in ghana - the ghana randomized air pollution and health study, or graphs - to assess how early life air pollution exposure and metals exposures affect cardiovascular health through age 12 years. We will use well-established, validated methods to assess these outcomes. In the long run, our research will help build the evidence base for cost effective interventions to improve health by reducing HAP exposure.

Transactions

Action Obligated Date
Amendment $123,916
Amendment $444,312
Amendment $444,312
Amendment $181,259
Amendment $43,810
Amendment $351,860
Amendment $61,336
Amendment $61,336
Amendment $61,336
Amendment $61,336
Amendment $539,825
Amendment $539,825
Amendment Developing climate cohorts to understand health associations and resilience and susceptibility factors in ghana $572,729
Amendment $580,618
Amendment Developing climate cohorts to understand health associations and resilience and susceptibility factors in ghana $580,618
Amendment $618,733
Original award $618,733
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Subawards

Subrecipient Amount Awarded
Kintampo Health Research Centre The objective of the current research is to evaluate associations between prenatal and early life household air pollution exposure, and a clean cookstove… $181,259
Kintampo Health Research Centre The objective of the current research is to evaluate associations between climate and health leveraging two unique cohorts – the Kintampo Demographic… $113,224
Kintampo Health Research Centre The objective of the current research is to evaluate associations between prenatal and early life household air pollution exposure, and a clean cookstove… $445,516
The Trustees Of Columbia University In The City Of New York Year 1-3: 0255-G991-4609 Year 4: IF129091117-940002 Columbia University will collaborate with Kintampo Health Research Centre (KHRC) and Icahn School of… $979,736

Quick answers

Who received award R01ES034433?

R01ES034433 was awarded to Icahn School Of Medicine At Mount Sinai by National Institute of Environmental Health Sciences (National Institutes of Health) on September 7, 2022.

How much is award R01ES034433 worth?

$5,885,894 has been obligated on R01ES034433.

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