Project Grant R01EB038701
- The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $650,556 Project Grant under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to Northwestern University. The objective of this award is to develop an implantable sensor to enable precise examination of gastric motility in small animal models. The proposed research aims to: 1) Develop a miniature implantable, wireless device for chronic monitoring of...
- This federal Cooperative Agreement award is provided by the National Institute of Neurological Disorders and Stroke, part of the National Institutes of Health, under the Drug Use and Addiction Research Programs (CFDA 93.279). The $451,297 award is intended to support research on using Gastric Electrical Stimulation (GES) to help treat abdominal pain in patients with gastroparesis, a condition affecting over 5 million Americans. The research will investigate two novel GES parameter settings, PP...
- This $199,208 Project Grant awarded by the National Science Foundation's (NSF) Engineering program (CFDA 47.041) supports research to develop a multiscale, physics-based electromechanical modeling framework for understanding stomach motility and structure. The 2-year project conducted by Kennesaw State University Research And Service Foundation, Inc. aims to characterize the stomach's layered structure and heterogeneous mechanical properties to advance digital twin models for diagnosing and...
- This National Science Foundation (NSF) Project Grant, awarded under the Computer and Information Science and Engineering (CISE) program (CFDA 47.070), provides $168,690 to the Florida Institute of Technology Inc. (Florida TECH) to develop a theragnostic (therapeutic + diagnostic) system for inflammatory bowel diseases (IBD). The project aims to model the complex interplay of host, microbial, and environmental factors that trigger IBD using data science, and then leverage synthetic biology and...
- This $202,728 federal Project Grant awarded by the National Science Foundation's (NSF) Computer and Information Science and Engineering (CISE) program funds a collaborative research project to develop a theragnostic (therapeutic and diagnostic) system for inflammatory bowel diseases (IBD). The project aims to integrate data science, synthetic biology, and additive manufacturing to model the complex interplay of host, microbial, and environmental factors in IBD, and develop an engineered...
- This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847) aims to study the use of transcranial magnetic stimulation (TMS) to modulate brain-to-stomach neural circuits and treat chronic nausea and vomiting syndrome (CNVS). The $656,104 award to the University of Pittsburgh will map the cortical regions that influence gastric electrical function, and then use stimulatory and inhibitory TMS to modulate these regions and assess the impacts on...
- This Project Grant award, valued at $206,132 and provided by the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), aims to develop a wireless, battery-free bioelectronic implant for closed-loop neuromodulation to treat detrusor sphincter dyssynergia (DSD) in individuals with spinal cord injury. The University of Houston System, the awardee, will fabricate and...
- This Project Grant award from the National Science Foundation (NSF) Engineering program (CFDA 47.041) to Georgia TECH Research Corp provides $499,896.00 to develop an artificial nervous system for communication between wearable and implantable biomedical devices. The project aims to optimize emitter and receiver networks to enable coordination of sensors and therapeutic actuators throughout the body, with potential applications in areas like sciatic nerve stimulation and controlled drug...
- This $354,066 federal Project Grant award from the National Science Foundation (NSF) Engineering program (CFDA 47.041) will support the development of a smart and connected robotic system for comprehensive diagnosis of abnormal tissues in the abdominal cavity. The award will fund research across three main thrusts: 1) integrating a multimodal instrument with balloon-based ultrasound and Raman spectroscopy capabilities to detect, classify, and stage tissue; 2) developing a tendon-driven continuum...
- This federal Project Grant award of $524,837 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) is supporting research to investigate the role of enteric glial mechanotransduction and the impact of mechanical stress on postoperative ileus (POI) and postoperative gastrointestinal dysfunction (POGD). The research aims to better understand the pathogenic mechanisms of POI in...
This federal Project Grant award of $296,746 from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) aims to develop an intelligent adaptive closed-loop system called "CyberGut" that can identify and deliver optimized electrical stimulation to restore normal gastric motility in patients with gastric disorders. The key products to be developed under this 4-year project include: 1) a network of millimeter-scale wireless "gastric seed" devices implanted in the stomach to record and stimulate gastric activity; 2) a wearable unit for wirelessly powering and communicating with the gastric seeds; and 3) computational organ modeling and machine learning algorithms to inform the closed-loop control system. This research seeks to overcome limitations of current open-loop gastric electrical stimulation therapies and advance the understanding and treatment of gastrointestinal disorders.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $296.7k | 8/7/25 |