Prism-pet: a TOF-DOI-compton pet detector technology for total-body pet imaging

Ended Project Grant Awarded Last action

Award ID
R01EB030413
Recipient
Awarding agency
Obligated
$6,233,799

Award facts

Completion date
Originally
Funding
  • $5,586,634.00 Federal
  • $647,165.00 Non-federal
Place of performance
Stony Brook, NY 11794, USA

Award details come from USAspending.gov.

Description

Abstract
The relatively small axial field-of-view (FOV) in almost all pet scanners has severely limited their sensitivity and resulted in significant tradeoffs between image signal-to-noise ratio (SNR), acquisition time, and delivered dose. The solution is to improve geometric coverage using large axial FOV for total-body imaging which has the potential to improve sensitivity by about 40 times compared to existing commercial whole-body pet scanners. The construction of the world's first total-body pet/CT scan-NER, called explorer, with 194-CM axial FOV has recently been completed. However, IT has a poor time-of-flight (TOF) resolution of 430 PS, compared to the state-of-the-art whole-body pet scanner with 200 PS timing resolution (siemens biograph vision). In addition, axial detector penetration of obliquely incident gamma photons detected within this wide acceptance angle will introduce significant depth-of-interaction (DOI) parallax error, leading to degraded spatial resolution. These two major defi-ciencies of the explorer scanner offset its effective sensitivity gain, specially for imaging single organs such as the human brain when compared to the biograph vision pet scanner. For this research, we propose to build cost-effective block detectors with combined highest spatial resolution (2 MM), highest TOF resolution (

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Subawards

Subrecipient Amount Awarded
Suny Stony Brook Medical Imaging with Weill Cornell Medicine “Prism-PET: A TOF-DOI-Compton PET detector technology for total-body PET imaging” Budget Justification – Dr. Wei… $241,903
The Research Foundation For The State University Of New York Dr. Zhao has been working on the development and advanced clinical applications of radiation detectors for cancer imaging for more than 25 years. She have… $215,050
Petsys Electronics - Medical Pet Detectors, S.A. PETsys (Contact PI: Dr. Stefaan Tavernier $93,613
Brookhaven Science Associates LLC The goal of this project is to develop new and improved detectors for use in Time-of-Flight PET through a collaboration between the Physics Department at… $2,150,520

Quick answers

Who received award R01EB030413?

R01EB030413 was awarded to The Research Foundation For The State University Of New York by National Institute of Biomedical Imaging and Bioenginering (National Institutes of Health) on May 1, 2021.

How much is award R01EB030413 worth?

$6,233,799 has been obligated on R01EB030413: $5,586,634 in federal funding and $647,165 in non-federal funding.

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