Project Grant R01DK148868
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded the University of Arkansas for Medical Sciences $717,457 on February 15, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to investigate metabolic rewiring of T cells and the pathogenic connection between diabetes and hypertension. The research examines immune-metabolic crosstalk in the progression from type 2 diabetes to hypertension using a high-fat diet-induced...
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded The Washington University $720,353 on March 25, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847, Assistance Listing Project Grant R01DK141555). The award funds research to identify and elucidate the functioning of hypothalamic neural circuits that regulate energy balance and metabolism, with focus on obesity-associated metabolic diseases. The research targets a...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded the University of Alabama at Birmingham $743,243 on August 1, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to conduct a sequential multiple assignment randomized trial optimizing intensive behavioral therapy for obesity in adults aged 50 to 75 years. The trial will enroll 250 adults with obesity to determine the optimal first-line diet strategy—high-protein versus...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded New York University a Project Grant of $861,091 on September 4, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The recipient will conduct neuroimaging and computational modeling research to identify the neural and decision-making mechanisms underlying loss-of-control eating and obesity. The research applies a novel framework positing that failures in self-control...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded Texas Woman's University $133,175 on September 1, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to investigate the role of DHRS9 in diet-induced obesity and diabetes. The research project will define how DHRS9 modulates insulin sensitivity under high-fat diet conditions across sexes and determine whether retinoid or specialized pro-resolving mediator (SPM)...
- The National Institute of Diabetes and Digestive and Kidney Diseases, part of the National Institutes of Health under the Department of Health and Human Services, awarded $717,030 to the University of Virginia on May 1, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to uncover neural circuits controlling body weight and metabolism. The research develops and applies RAMPANT (rabies afferent mapping by poly-A nuclear transcriptomics), a novel...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded the University of Virginia $782,459 on March 1, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to investigate the impact of obesity on microvascular insulin action and cardiorespiratory fitness in individuals with Type 1 Diabetes. The research will test the hypothesis that endothelial oxidative stress and microvascular insulin resistance lead to reduced skeletal and...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded Duke University $790,119 on August 26, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to investigate how memory formation in adipose tissue influences metabolic outcomes in obesity. The project, titled "Establishing Memory in Adipose Tissue Influences Future Metabolic Outcomes in Obesity," examines the mechanisms that drive divergent remodeling of white...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded The Trustees of the University of Pennsylvania $100,228 on December 1, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award funds research on fibroadipogenic progenitor cell regulation of skeletal muscle recovery after injury and metabolic responses to whole-body weight loss. The research addresses how fibroadipogenic progenitor cells—tissue-resident...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded The Leland Stanford Junior University $782,886 on February 18, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to support research on obesity control through an appetite-suppressing peptide. The research addresses the urgent need for new metabolies, including obesity and associated metabolic disorders. Work is performed in Palo Alto, California with a period of...
The National Institute of Diabetes and Digestive and Kidney Diseases awarded Arkansas Colleges of Health Education $646,459 on September 1, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to conduct research on novel mechanisms promoting energy intake compensation in response to aerobic and resistance exercise. The research addresses how individuals compensate for energy expended during exercise by increasing food intake, thereby limiting weight loss—a key barrier to obesity treatment. The study compares weight loss and body composition outcomes between aerobic exercise alone and combined aerobic plus resistance exercise training matched on energy expenditure, and seeks to elucidate the physiological mechanisms driving exercise-induced increases in energy intake between the two intervention groups. The research is motivated by the prevalence of overweight and obesity in over 70 percent of Americans and the limited pharmacological treatment access many individuals face. Performance occurs in Fort Smith, Arkansas, with a period of performance from September 1, 2026, through May 31, 2031. The assistance type is a Project Grant, a standard NIH research award mechanism supporting basic and clinical biomedical research that improves understanding of disease mechanisms and leads to improved prevention, diagnosis, and treatment of diabetes, digestive, and kidney diseases.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $0 | 9/2/26 | ||
| Not listed | $646.5k | 9/1/26 |