Project Grant R01DK140224
- This federal Project Grant award, funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $3,005,541.00 to Baylor College of Medicine to conduct research on the mechanisms driving age-dependent and sex-dependent changes in bladder immunity that contribute to recurrent urinary tract infections (UTIs) and other lower urinary tract disorders in older women. The...
- This Project Grant award of $226,253 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), aims to elucidate the adaptations of Staphylococcus aureus that enable its persistence within the bladders of long-term catheterized individuals. The research will be conducted by the University of Texas Health Science Center at Houston (UTHealth) from September 1, 2025 through...
- This $117,000 Project Grant award was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), to the Research Institute at Nationwide Children's Hospital. The project aims to define the mechanisms by which the transcription factor STAT3 contributes to antimicrobial host defense in the human urothelium (bladder lining) against urinary tract infections (UTIs). Key...
- This $809,427 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), supports research on the impact of polymicrobial interactions and within-host adaptation on the pathogenesis of catheter-associated urinary tract infections (CAUTI). The award recipient, The Research Foundation For The State University Of New York (RF SUNY) doing business as Sponsored...
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $320,778 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to the University of Vermont & State Agricultural College. The project, titled "PACAP/PAC1R Signaling and CRH Intersections in Micturition Circuits: Effects of Stress and Injury/Inflammation," will investigate how changes in central micturition and peripheral sensory circuits due to...
- This Project Grant award from the Department of Health and Human Services National Institutes of Health (CFDA 93.310 Trans-NIH Research Support) is providing $323,850.00 to Watershed Medical Inc. to develop an innovative drug delivery platform for local delivery of the antibiotic amikacin to the bladder. The goal is to create a prophylactic solution to treat and prevent recurrent urinary tract infections (rUTIs) in post-menopausal women. Initial human studies have demonstrated the product's...
- This federal Project Grant award for $390,000 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award aims to study the impact of step therapy utilization management strategies on access to care for patients with overactive bladder (OAB), as well as evaluate alternative patient-centered treatment approaches. Key objectives include using electronic health...
- This federal Project Grant award of $432,625 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The purpose of the grant is to create a dataset measuring urological function in 8 different rat strains at various life stages. This dataset, combined with previous data, will help researchers understand how urological function differs across rat strains and guide...
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $176,201 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to the University of California, Irvine. The grant, with an award date of July 15, 2025 and an ultimate completion date of March 31, 2030, will fund research to investigate the molecular changes in aging female urethral striated muscle and develop potential treatments for urethral dysfunction,...
- This federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $708,138 to support the development of a biomechanocompatible small molecule-releasing scaffold for bladder augmentation. The goal is to create an alternative to conventional surgical approaches that use detubularized bowel tissue, which can have significant complications. The...
This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $653,123 to The University of Texas Southwestern Medical Center (UT Southwestern) to conduct a multi-center randomized trial comparing daily nitrofurantoin versus bladder fulguration plus daily nitrofurantoin for the long-term management of cystitis in women with recurrent urinary tract infections (rUTIs). The study aims to investigate strategies for reducing the burden of rUTIs, which can have significant physical and psychological impacts. This award runs from September 1, 2025 through June 30, 2030 and builds on UT Southwestern's prior research on the use of bladder wall electrofulguration to treat chronic cystitis and rUTIs.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $653.1k | 8/26/25 |