This Project Grant award, valued at $689,177.00 and issued on Jul 22, 2024, was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award aims to uncover the complex relationships between environmental, genetic, and 'omic factors in the development of Type 2 Diabetes (T2D). Key objectives include: 1) Developing software to identify differences in the effects of...
This $1,286,116 Cooperative Agreement award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), will support a project titled "Metabolomic and Genomic Expansion of Type 2 Diabetes Subtyping in Multiethnic Populations." The project aims to assemble, harmonize, and integrate clinical, genetic, metabolomic, and social determinants of health data from 10 diverse...
This $734,221 Project Grant, awarded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), supports genetic investigations into cardiometabolic diseases at the University of California, San Diego (UCSD). The research aims to enhance biological insights into the shared risk factors and pathophysiology underlying conditions such as coronary artery disease, stroke, type 2...
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $823,473 Cooperative Agreement under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to The General Hospital Corporation (Massachusetts General Hospital) to study longitudinal omics-based trajectories of type 2 diabetes subtypes. The five-year project aims to use multi-omic data to refine definitions of prediabetes and type 2 diabetes, describe associations between...
This $711,791 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) will fund a large longitudinal cohort study focused on understanding the epidemiology and risk factors for type 2 diabetes among Asian American, Native Hawaiian, and Pacific Islander (AANHPI) adolescents and young adults. The study, led by the Kaiser Foundation Research Institute, will...
This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $12,847,914 in funding to Emory University to study the Alzheimer's disease (AD) and Alzheimer's-related dementias (ADRD) continuum in middle-aged South Asians in India. The key objectives are to: 1) Perform multimodal AD/ADRD phenotyping and genetic characterization across the disease continuum; 2) Investigate modifiable risk factors (socio-behavioral, vascular, metabolic) associated with...
This federal Project Grant award for $714,440, provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), supports research to advance precision diabetes medicine. The key objectives are to: Define metabolic subphenotypes in prediabetes and early type 2 diabetes based on underlying physiologic defects, including insulin resistance, beta-cell function, incretin effect, and...
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $575,394 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH). The 5-year grant, commencing on August 1, 2024, will support research to develop a multi-ancestry polygenic risk score for predicting type 1 diabetes (T1D) and related immune-mediated forms of diabetes....
This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) provides $248,915 to the University of Maryland, Baltimore to conduct research aimed at "Unravelling the Role of Epigenetics and Cytokines in Type 2 Diabetes Among African-Ancestry Populations." The key objectives are to infer causality in the relationships between lifestyle factors,...
This $784,636 Cooperative Agreement award was granted by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The primary goal is to develop a standardized classification system to define new subtypes of type 2 diabetes (T2D) using a combination of clinical variables, genetics, and metabolomics data. The awardee, The General Hospital Corporation (doing business as Massachusetts...