Project Grant R01DK137775
Award Date
8/15/24
Completion Date
6/30/28
Dollars Obligated
$850K
Federal Grant Program
93.847
Assistance Type
Project Grant
Place of Performance
Chicago, IL 60611, USA
Similar Awards
This Project Grant award of $964,718 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under CFDA 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research will fund research at Northwestern University to develop and validate a "Virtual Esophagus" (VESOPHAGUS) simulation model. The goal is to leverage this model to define the physiomechanical factors driving poor outcomes in patients with achalasia and gastroesophageal reflux disease (GERD),...
This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) provides $594,956 to the University of South Florida to conduct research on the mechanisms underlying stretch-evoked activation of esophageal vagal afferents. The goal is to determine the mechanosensitive channels and sodium channels responsible for transducing esophageal stretch into vagal afferent...
This $475,605 Project Grant award was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant aims to definitively evaluate gastric dysrhythmia as a disease mechanism underlying functional dyspepsia and chronic nausea/vomiting syndromes, which affect over 10% of the population. The project will apply a novel non-invasive diagnostic approach called Body...
This Cooperative Agreement award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), will fund a $389,578 multi-center clinical research project focused on improving the treatment of achalasia, a rare esophageal motility disorder. The project, titled "Precision Medicine in Achalasia - PREMEDIA", aims to test an innovative, tailored approach to per-oral endoscopic...
This Project Grant award of $949,056, provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), supports research by Northwestern University to investigate the functional roles of the DDX41 gene in the homeostasis of G-quadruplexes during erythropoiesis. The research aims to elucidate the molecular and cellular mechanisms by which DDX41 mutations contribute to the...
This $188,538 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) supports research at Northwestern University to develop predictive modeling of chromatin packing domains for personalized biomarker discovery in ulcerative colitis. The goal is to establish a framework linking transcriptomic states with chromatin structure to advance biomarker development. The research project...
This federal Project Grant award of $524,837 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) is supporting research to investigate the role of enteric glial mechanotransduction and the impact of mechanical stress on postoperative ileus (POI) and postoperative gastrointestinal dysfunction (POGD). The research aims to better understand the pathogenic mechanisms of POI in...
This federal Project Grant award, funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $747,500.00 to support research on memory formation in the enteric nervous system (ENS). The project aims to build the tools required for studying the formation and meaning of ENS memories, and then use these tools in combination with various perturbations to transform the...
This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $191,234 to Beth Israel Deaconess Medical Center, Inc. over the period of August 1, 2025 to July 31, 2030. The funding supports research to examine the role of gastric dopaminergic signaling and gastrointestinal mucosal injury in Parkinson's disease. Key objectives include investigating...
This Project Grant award of $117,000.00 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) supports research to investigate the role of substance P-mediated activation of mast cells in driving visceral hypersensitivity and barrier dysfunction in irritable bowel syndrome (IBS). The objective is to delineate the underlying mechanisms of bidirectional crosstalk between sensory...