Project Grant R01DE035894
- Federal Project Grant Award Summary The National Institute of Dental and Craniofacial Research awarded the University of Michigan Regents a $379,320 Project Grant on September 11, 2025, under the Trans-NIH Research Support program (CFDA 93.310) to develop noninvasive diagnostic methods for periodontal disease detection. The research deliverables include the establishment of ultrasound-derived quantitative biomarkers and a machine learning classifier for characterizing inflammatory conditions...
- Federal Grant Award Summary The National Institute of Dental and Craniofacial Research (NIDCR) awarded the University of Florida's Division of Sponsored Research a Project Grant of $325,176 on August 8, 2025, under the Oral Diseases and Disorders Research program (CFDA 93.121) to develop artificial intelligence (AI)–derived multilevel social risk scores for oral cavity and oropharyngeal cancer (OCC/OPC) patients. The research addresses critical gaps in timely diagnosis and treatment access for...
- Federal Project Grant Award Summary The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $315,000 Project Grant to The University of Texas Health Science Center at San Antonio effective August 20, 2025, through August 19, 2027, under the Oral Diseases and Disorders Research program (CFDA 93.121). This award supports research to develop and validate a novel therapeutic approach targeting Transient Receptor Potential Canonical 1 (TRPC1) channels as a treatment for oral...
- Federal Project Grant Award Summary The National Institute of Dental and Craniofacial Research (NIDCR) awarded a Project Grant of $1,245,488 to The University of Texas Health Science Center at San Antonio under the Oral Diseases and Disorders Research program (CFDA 93.121) effective July 1, 2025, through March 31, 2030. This research project investigates the role of TRPM2 (Transient Receptor Potential Melastatin 2), a calcium-permeable ion channel, in the pathogenesis of radiation-induced oral...
- Federal Grant Award Summary The National Science Foundation's Division of Mathematical Sciences awarded a $300,011 Project Grant to the Regents of the University of California at Riverside on September 15, 2025, under the Mathematical and Physical Sciences program (CFDA 47.049). This collaborative research project will develop novel mathematical and statistical methodologies to establish trustworthy artificial intelligence (AI)-driven frameworks for constructing reliable and personalized digital...
- Federal Project Grant Award Summary The National Institute of Dental and Craniofacial Research (NIDCR) awarded The University of Texas Health Science Center at San Antonio $449,861 under the Oral Diseases and Disorders Research program (CFDA 93.121) to conduct a 24-month clinical observational feasibility study examining dental practitioners' oral appliance therapy (OAT) titration methods for obstructive sleep apnea (OSA) and their associated patient outcomes. Initiated on June 17, 2025, the...
- Federal Project Grant Award Summary The National Institute of Dental and Craniofacial Research (NIDCR) awarded $1.47 million to The University of Texas MD Anderson Cancer Center in Houston, Texas on March 1, 2026, under the Oral Diseases and Disorders Research program (CFDA 93.121) for a five-year project titled "Elucidating Subclonal Evolution and Fitness Dynamics in Oral Carcinogenesis." The research initiative addresses critical gaps in understanding how oral premalignant lesions...
- Federal Grant Award Summary The National Institute of Dental and Craniofacial Research (NIDCR) awarded the University of Pittsburgh a $673,091 Project Grant on August 14, 2025, under the Oral Diseases and Disorders Research program (CFDA 93.121) to advance the genomics knowledge base for oral diseases. This award supports the formation of a large-scale research consortium encompassing over 800,000 research participants across at least 27 studies to conduct the largest genome-wide association...
- Federal Grant Award Summary The National Institute of Dental and Craniofacial Research (NIDCR) awarded Cleveland Clinic Lerner College of Medicine of Case Western Reserve University a Project Grant in the amount of $568,759 under the Oral Diseases and Disorders Research program (CFDA 93.121). The award, effective May 1, 2026, through April 30, 2031, funds research investigating pathogen synergy and immune subversion mechanisms in periodontal disease. The project delivers scientific research...
- Federal Project Grant Award Summary Temple University received a $438,768 Project Grant from the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121), awarded August 14, 2025, with a completion date of August 13, 2027. This grant supports research addressing oral health disparities among underserved populations, including Hispanics, Non-Hispanic Blacks, and rural Non-Hispanic Whites, who experience significantly...
The University of Texas Health Science Center at Houston received a $578,830 Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121), effective May 15, 2026, with a completion date of February 28, 2031. The award funds the PREDICT project, which develops and validates an artificial intelligence (AI)-driven diagnostic and clinical decision support (CDS) system designed to improve periodontitis diagnosis and risk stratification in real-world dental practice settings. The project addresses a significant public health challenge, as periodontitis affects 42% of U.S. adults and current diagnostic methods suffer from high misclassification rates (32%). The research comprises three coordinated aims: Aim 1 creates AI models integrating multi-modal dental imaging (2D and 3D) for precise diagnostic assessments, validated using retrospective data from Willamette Dental; Aim 2 develops machine learning algorithms using longitudinal electronic health record (EHR) data to predict periodontitis development and progression; and Aim 3 deploys the refined models from Aims 1 and 2 into a prospective, phased pilot study to evaluate the clinical CDS tool. These integrated efforts will produce validated AI models and a functional clinical decision support tool to reduce diagnostic variability and improve patient treatment outcomes.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $578.8k | 5/18/26 |