A wireless micro-ecog prosthesis for speech

Active Project Grant Awarded Last action

Award ID
R01DC019498
Recipient
Awarding agency
Obligated
$5,129,889

Award facts

Completion date 86% complete
Originally
Funding
  • $4,474,293.00 Federal
  • $655,596.00 Non-federal
Place of performance
Durham, NC 27708, USA

Award details come from USAspending.gov.

Description

As the agency reported it.

Abstract
Patients who suffer from debilitating neuromuscular disorders (e.g. amyotrophic lateral sclerosis - ALS, locked- in-syndrome - LIS, and muscular dystrophies/myopathies) have difficulty or an inability to communicate through speech leading to a detrimental loss in quality of life. Current technology using eye movements and signals/spellers from electroencephalography (EEG) are slow and inconsistent. Neural prostheses offer an opportunity to produce fast and accurate communication for patients suffering from neuromuscular disorders, but success for regaining speech has been limited due to technological limitations: there is an inability to capture the high dimensionality of the brain and an inability to record in naturalistic conditions using fully implanted, wireless electrode arrays. To solve these challenges, we develop and optimize custom wireless micro- electrocorticographic (μecog) arrays with over 1,000 channels to decode speech directly from the human brain. We will accomplish this by 1) testing and optimizing the spatial resolution of μecog to capture neural signals, 2) fine-tune our machine learning algorithms to decode speech directly from the brain and 3) developing wireless technology to enable neural prosthetic usage in naturalistic settings. High-density, high channel-count neural interfaces will offer an unprecedented ability to decode speech from the human brain. This ability combined with wireless technology, will allow for a new generation of speech neural prostheses.

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Subawards

Subrecipient Amount Awarded
Blackrock Microsystems, Inc. Blackrock Neurotech will provide support for the grant including performing the following tasks as requested by the PI: Provide regulatory oversight of proposed… $324,616
The Trustees Of Columbia University In The City Of New York Providing access and supporting use of ASICs for wireless electrophysiology $414,000
University Of Utah The goal of the project is to develop and demonstrate a novel, high channel electrode for the use in a neural speech prosthesis for the use in patients… $184,176

Quick answers

Who received award R01DC019498?

R01DC019498 was awarded to Duke University by National Institute on Deafness and Other Communincation Disorders (National Institutes of Health) on September 17, 2021.

How much is award R01DC019498 worth?

$5,129,889 has been obligated on R01DC019498: $4,474,293 in federal funding and $655,596 in non-federal funding.

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