Project Grant R01DC017159

This Project Grant award from the National Institute on Deafness and Other Communication Disorders (NIDCD), under the Research Related to Deafness and Communication Disorders federal grant program (CFDA 93.173), will fund research to investigate how temperature affects the perception of salt taste and its neural processing in the cortex of behaving mice. The total award of $129,142 will support a behavioral study to determine how temperature impacts the ability to discriminate between the...

This Project Grant award of $174,418.00 from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), supports research to determine the function of TRP-positive trigeminal sensory neurons innervating the submandibular salivary glands. The objective is to understand how this direct sensory innervation of the submandibular glands by trigeminal neurons contributes to the regulation of saliva production and...

This Project Grant award of $773,887.00 was provided by the National Science Foundation (NSF) under the Biological Sciences Federal Grant Program (CFDA 47.074) to the Board of Regents of the University of Nebraska. The goal of this 5-year research project is to identify the specific roles that zinc plays in the sensation of taste. The research will use gene expression studies, cell physiology, histology, taste nerve recordings, and taste behavior analysis in mice to understand how zinc...

The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $491,193 Project Grant under the Oral Diseases and Disorders Research program (CFDA 93.121) to the University of California, San Diego (UCSD) for the project "Engineering Mucin Analogues to Benefit the Mouth Environment." The project aims to create advanced mucin substitutes that closely emulate the physiological functions of natural salivary mucins, in order to develop enhanced artificial saliva...

This $412,077 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports research by Colorado State University to investigate the role of SLO2 potassium channels in olfactory adaptation. The key objectives are to genetically manipulate the expression of the SLO2 channel in the fruit fly model system, test for impacts on olfactory adaptation in vivo,...

This $429,000 Project Grant awarded by the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121) will fund research to evaluate the therapeutic potential of targeting phosphodiesterase-4 (PDE4) enzymes as a novel approach to alleviate symptoms and address the underlying causes of salivary gland dysfunction and xerostomia (dry mouth) associated with Sjögren's syndrome. The research will be conducted by the University of...

This Project Grant award, funded by the National Institute on Deafness and Other Communication Disorders (NIDCD) under the Research Related to Deafness and Communication Disorders program (CFDA 93.173), supports scientific research to investigate the interactions between the gustatory thalamus and gustatory cortex in the neural processing of taste perception and behavior. The $413,123 award, with a project period from September 19, 2024 to August 31, 2026, will be performed by Brandeis...

This $461,889 federal Project Grant award was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The grant supports research by the University of Iowa to study the mechanisms regulating the activity of NTSHSD2 neurons, which are involved in the control of sodium appetite. The research aims to: 1) Determine how aldosterone-mineralocorticoid receptor...

This Project Grant award from the National Institute on Deafness and Other Communication Disorders (NIDCD), under the CFDA Program 93.173 "Research Related to Deafness and Communication Disorders," provides $429,000.00 to the University of Colorado-Denver to establish human lingual organoid models as a platform for studying taste bud function and perturbations. The key objectives are to: 1) validate and characterize circumvallate papillae samples from male and female human donor tissue...

The National Science Foundation (NSF) Engineering program (CFDA 47.041) has awarded a $408,653 Project Grant to The Ohio State University for the "E-TASTE, AN IOT-ENABLED GUSTATORY INTERFACE FOR REMOTE CHEMICAL INTERACTION" research project. The goal of this 3-year project is to develop a gustatory (taste) interface integrated with an Internet of Things (IoT) framework to support remote human-human interaction, with a focus on potential medical applications where remotely...