Project Grant R01CA309492
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded University of Miami a $2.75M Project Grant on September 12, 2025, under the Cancer Cause and Prevention Research program (CFDA 93.393) to conduct a four-year clinical research study examining the effects of remotely-delivered cognitive behavioral stress management (R-CBSM) on cancer-accelerated aging in distressed breast cancer survivors aged 50 and older. The study will enroll 192 breast cancer survivors who completed...
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded a Project Grant of $716,521 to Sloan-Kettering Institute for Cancer Research on August 25, 2025, under the Cancer Treatment Research program (CFDA 93.395). The award supports the development and clinical evaluation of DLL3-targeted IL18-secreting chimeric antigen receptor (CAR) T cells for treating small cell lung cancer (SCLC). The research initiative addresses a critical clinical need, as SCLC currently demonstrates...
- Federal Project Grant Summary The National Cancer Institute awarded $696,498 to the MGH Institute of Health Professions, Inc. on May 1, 2026, under the Cancer Cause and Prevention Research program (CFDA 93.393) to develop and optimize a multicomponent intervention designed to improve functional recovery and participation in life activities among breast cancer survivors. The project, spanning five years through April 30, 2031, will systematically develop an evidence-based, remotely-delivered...
- Federal Project Grant Award Summary The National Cancer Institute awarded $292,028 to Sloan-Kettering Institute for Cancer Research under the Cancer Research Manpower program (CFDA 93.398) beginning August 1, 2025, and concluding July 31, 2030. This five-year Project Grant supports research investigating genome instability associated with focal oncogene amplification (OA) and the development of therapeutic strategies to address treatment-resistant cancers. The research deliverables include...
- Federal Project Grant Award Summary The National Cancer Institute awarded a $730,398 Project Grant to the Sloan-Kettering Institute for Cancer Research (Award Date: April 1, 2026; Completion Date: March 31, 2031) under the Cancer Treatment Research program (CFDA 93.395). This research initiative aims to develop novel therapeutic approaches targeting tumor regenerative cells (TRCs) that drive resistance to total neoadjuvant therapy (TNT) in locally advanced rectal cancer (LARC). The project...
- Federal Project Grant Award Summary The National Cancer Institute awarded a Project Grant of $418,176.00 to Sloan-Kettering Institute for Cancer Research under the Cancer Biology Research program (CFDA 93.396) for the period September 1, 2025, through August 31, 2028. This three-year award supports the advanced development and validation of programmable nucleic acid cytometry, a technology designed to isolate and profile rare cell populations from tumors and tissues. Building on the...
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded The Regents of the University of Colorado a $656,046 Project Grant on August 1, 2025, under the Cancer Cause and Prevention Research program (CFDA 93.393) to conduct a randomized controlled trial of EASE (Exposure-based Anxiety and Symptom Elimination), a novel behavioral intervention designed to reduce fear of cancer progression (FOP) and cancer-related trauma symptoms in adults with advanced cancer. The five-year...
- Federal Grant Award Summary The National Cancer Institute awarded a $2.49M Project Grant under the Cancer Biology Research program (CFDA 93.396) to the Sloan-Kettering Institute for Cancer Research, effective August 1, 2025, through July 31, 2030. This research initiative comprises three integrated projects investigating lipid metabolism as a determinant of ferroptosis sensitivity in cancer cells. Project 1, led by Dr. Xuejun Jiang at Memorial Sloan Kettering Cancer Institute, examines how...
- Federal Project Grant Award Summary The National Cancer Institute (NCI) awarded $730,398 to Sloan-Kettering Institute for Cancer Research through the Cancer Treatment Research program (CFDA 93.395) on September 1, 2025, for a five-year project period concluding August 31, 2030. This Project Grant supports research and development activities designed to advance novel treatment approaches for rectal cancer, with emphasis on organ preservation strategies that minimize patient morbidity. The...
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded H. Lee Moffitt Cancer Center and Research Institute Hospital, Inc., a Project Grant of $734,942 under the Cancer Cause and Prevention Research program (CFDA 93.393) effective August 1, 2025, through July 31, 2030. This project addresses cardiovascular disease (CVD) risk in breast cancer survivors by generating novel DNA methylation biomarker data from the Pathways Study, a prospective cohort of 4,504 women diagnosed with...
The National Cancer Institute (NCI) awarded Sloan-Kettering Institute for Cancer Research a Project Grant of $731,503 under the Cancer Cause and Prevention Research program (CFDA 93.393) effective June 1, 2026 through May 31, 2031. This award supports a randomized controlled trial evaluating Brief Behavioral Activation for Older Adult Cancer Survivors (BBA-OACS), a modified psychotherapy intervention specifically designed to address depression and improve health outcomes in cancer survivors aged 65 and older. The research deliverables include development and testing of a cancer-specific BBA intervention manual with modified clinical worksheets emphasizing cancer survivorship self-efficacy and American Cancer Society-recommended preventive health behaviors, including healthy weight management, exercise, nutrition, and avoidance of alcohol and tobacco. The project addresses a significant clinical gap, as up to 35% of the estimated 73% of cancer survivors who will be 65 years or older by 2040 are expected to develop clinically significant depression. The study employs a fully remote delivery model utilizing telehealth, encompassing recruitment, intervention delivery, and assessment procedures. This intervention design addresses unique challenges faced by older adult cancer survivors, including fatigue, cognitive changes, mobility limitations, pain, and social isolation, while adapting to varying functional statuses that may be particularly relevant given the accelerated functional decline common in this population. The research aims to produce evidence supporting the integration of BBA-OACS into standard depression management protocols for older adult cancer survivors, particularly among Hispanic populations who demonstrate lower mental health service utilization despite elevated depression risk.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $731.5k | 6/1/26 |