Project Grant R01CA307143
- Federal Grant Award Summary The University of Wisconsin-Madison received a $2.58 million Project Grant from the National Cancer Institute under the Cancer Detection and Diagnosis Research Program (CFDA 93.394), awarded August 11, 2025, and extending through July 31, 2030. This multi-institutional research program investigates the molecular drivers and therapeutic susceptibilities in lineage state transitions of metastatic castrate-resistant prostate cancer (MCRPC). The project addresses critical...
- Federal Grant Award Summary The National Cancer Institute awarded the University of Wisconsin–Madison a $634,644 Project Grant on March 12, 2026, under the Cancer Treatment Research program (CFDA 93.395) to support research into treatment of neuroinflammation associated with chemoradiation-induced dysphagia. The research extends through February 28, 2031, and involves preclinical investigation using a rat animal model to evaluate the efficacy of glibenclamide (GLC) pharmaceutical intervention...
- Federal Grant Award Summary The University of Wisconsin-Madison received a $116,685 Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), effective September 1, 2025, through August 17, 2027. This award supports a two-phase research initiative examining cancer survivorship needs and reintegration outcomes for children with Down Syndrome (DS) who are in remission from...
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded The Medical College of Wisconsin, Inc. a Project Grant totaling $632,314 under the Cancer Treatment Research program (CFDA 93.395) effective April 1, 2026, through March 31, 2031. This award supports research and development of gallium maltolate (GAM), an iron-mimetic metallocompound, as a novel therapeutic intervention for difficult-to-treat pediatric central nervous system (CNS) tumors, specifically pediatric high-grade...
- Federal Grant Award Summary The National Cancer Institute awarded a $639,295 Project Grant to the Research Institute at Nationwide Children's Hospital on May 8, 2026, under the Cancer Cause and Prevention Research program (CFDA 93.393). This award supports a five-year research initiative extending through April 30, 2031, focused on elucidating the molecular mechanisms governing fusion oncoproteins derived from FET (Fused in Ewing sarcoma, Ewsr1, Taf15) family members fused to ETS transcription...
- Federal Project Grant Award Summary The University of Wisconsin-Madison received a $630,171 Project Grant award from the National Cancer Institute under the Cancer Treatment Research program (CFDA 93.395), effective August 12, 2025, with a completion date of July 31, 2030. The award supports the development of targeted radiopharmaceutical therapies (RPTs) for triple-negative breast cancer (TNBC), an aggressive breast cancer subtype that lacks expression of estrogen receptor, progesterone...
- Federal Project Grant Award Summary The National Cancer Institute (NCI) awarded the University of Miami's Office of Research Administration within the School of Medicine a Project Grant totaling $109,076.00 under the Cancer Research Manpower program (CFDA 93.398) on December 17, 2025. The award supports biomedical research training and career development initiatives focused on cancer research through September 1, 2029. This project grant funds the institution's capacity to provide integrated...
- Federal Project Grant Award Summary The University of Wisconsin–Madison received a $216,013 Project Grant award from the National Cancer Institute under the Cancer Biology Research program (CFDA 93.396) effective September 1, 2025, through August 31, 2027. This research project investigates the mechanisms by which Kaposi's sarcoma-associated herpesvirus (KSHV) hijacks cellular caspase enzymes to suppress interferon responses and develop targeted therapeutic strategies to block viral...
- Federal Project Grant Award Summary St. Jude Children's Research Hospital Inc. received a $491,925 Project Grant from the National Cancer Institute under the Cancer Treatment Research program (CFDA 93.395) for the period of June 1, 2026 through May 31, 2028. This R21 grant funds the development of artificial intelligence (AI) and machine learning frameworks to estimate personalized symptom networks for childhood cancer survivors. The project will create interpretable AI models that identify...
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded The Regents of the University of Colorado a $656,046 Project Grant on August 1, 2025, under the Cancer Cause and Prevention Research program (CFDA 93.393) to conduct a randomized controlled trial of EASE (Exposure-based Anxiety and Symptom Elimination), a novel behavioral intervention designed to reduce fear of cancer progression (FOP) and cancer-related trauma symptoms in adults with advanced cancer. The five-year...
The National Cancer Institute awarded a $689,340 Project Grant to the University of Wisconsin-Madison on June 1, 2026, under the Cancer Cause and Prevention Research program (CFDA 93.393) to conduct a five-year research initiative examining symptom trajectories in children with advanced cancer. The project will define symptom patterns over time among pediatric patients aged 8-18 with metastatic, relapsed, or refractory cancer; identify biopsychosocial characteristics that distinguish patient subgroups; and examine associations between patient subgroups and health outcomes. This research addresses a critical gap in understanding symptom burden in an understudied population, as prior symptom trajectory research has primarily focused on early-stage pediatric cancer patients rather than those with advanced disease experiencing intensive therapeutic regimens. The project deliverables will include empirical data characterizing symptom experiences of children with advanced cancer to inform the shift from reactive to proactive, risk-stratified symptom management approaches in clinical practice. By identifying demographic, social, and physiologic risk factors contributing to symptom burden variability, the research will enable clinicians to better anticipate and intervene in symptom suffering before it becomes normalized by patients. The award supports research performance through May 31, 2031, at the University of Wisconsin-Madison's facilities in Madison, Wisconsin.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $689.3k | 5/25/26 |