The National Cancer Institute (NCI) awarded a $585,976 Project Grant (CFDA 93.395 - Cancer Treatment Research) to Providence Health & Services - Oregon to conduct research on enhancing the efficacy of radiation therapy by spatially restricting anti-TGFβ treatment to the tumor microenvironment. The research aims to determine the role of self-renewing stem-like CD8+ T cells in local and distant radiation response, and test a combination therapy of radiation and second-generation TGFβ-targeting therapeutics that restrict activity to the tumor to preserve these critical T cell populations. The award period is from April 1, 2025 to March 31, 2030. This work builds on the program's focus on innovative approaches to cancer prevention, diagnosis, and treatment across diverse cancer types.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $586.0k | 3/28/25 |