Project Grant R01CA286563
Award Date
9/1/24
Completion Date
8/31/29
Dollars Obligated
$795K
Federal Agency
National Cancer Institute
Federal Grant Program
93.394
Assistance Type
Project Grant
Place of Performance
New York, NY 10065, USA
Similar Awards
This Project Grant award from the National Cancer Institute (CFDA 93.395 - Cancer Treatment Research) provides $752,588 to the University of Maryland, Baltimore to conduct a 12-week randomized controlled trial studying the effects of time-restricted eating on cancer-related fatigue among survivors of hematological malignancies. The study will recruit 96 participants and assess patient-reported fatigue, circadian activity rhythms, and glucose metabolism. The project aims to provide initial...
The National Cancer Institute (NCI) awarded a $767,324 Cooperative Agreement (CFDA 93.396 - Cancer Biology Research) to the Van Andel Research Institute (VAI) in Grand Rapids, Michigan. The purpose of this 5-year award, effective April 1, 2025, is to investigate how dietary caloric restriction regulates anti-tumor immunity through its impact on CD8 T cell metabolism and fate in the tumor microenvironment. The research aims to determine the mechanisms by which caloric restriction boosts CD8 T...
The National Cancer Institute (NCI), through its Cancer Cause and Prevention Research program (CFDA 93.393), awarded a $1,504,098 Project Grant to the Sloan-Kettering Institute for Cancer Research on May 6, 2025. The grant supports a study to identify genetic determinants of radiation-associated contralateral breast cancer (CBC) and develop a comprehensive integrative model of genetic predisposition to radiation-associated CBC. The research leverages the resources of the WECARE study, a large...
The National Cancer Institute (NCI) awarded a $455,111 Project Grant under CFDA 93.393 "Cancer Cause and Prevention Research" to the Sloan-Kettering Institute for Cancer Research in New York. The 2-year grant, awarded on September 5, 2023, will support research to "Leverage the Hidden Genome to Recover the Missing Heritability of Cancer." The project aims to 1) estimate additional heritability that can be explained by the "hidden genome" (regions of unknown...
This $189,163 federal Project Grant award from the National Cancer Institute under the Cancer Cause and Prevention Research program (CFDA 93.393) aims to investigate the impact of dietary patterns and physical activity on survival outcomes for patients with renal cell carcinoma (RCC). The research team at Brigham & Women's Hospital, with the University of California, San Francisco as a sub-grantee, will leverage data from three large, prospective cohorts to comprehensively evaluate pre-...
The National Cancer Institute (NCI), under the Federal Grant Program "Cancer Research Manpower" (CFDA 93.398), awarded a Project Grant in the amount of $145,336 to the Sloan-Kettering Institute for Cancer Research located in New York. The grant, titled "Metabolically Reprogramming Hepatic Macrophages to Conquer Immune Desert Tumors," will fund research focused on reprogramming hepatic macrophages to overcome the "immune-desert" phenotype of B-catenin-driven...
This Project Grant award from the National Cancer Institute (NCI), under the Cancer Cause and Prevention Research program (CFDA 93.393), provides $588,359 to Drexel University to evaluate the efficacy of a multi-level intervention designed to promote adherence to the dietary guidelines for cancer prevention recommended by the World Cancer Research Fund and American Institute for Cancer Research. The 5-year study will randomize 236 index participants to either receive nutrition education or the...
The National Cancer Institute (NCI) awarded a $581,381 Project Grant under the Cancer Cause and Prevention Research program (CFDA 93.393) to the Sloan-Kettering Institute for Cancer Research. The 5-year grant, effective June 5, 2025, will fund research to investigate the role of microhomology-mediated end-joining (MMEJ) in mitosis and its impact on drug resistance in cancer. The key products of this research will be a better understanding of DNA damage repair pathways and how they contribute...
This Project Grant award from the National Cancer Institute (CFDA 93.393 - Cancer Cause and Prevention Research) provides $441,913 to Tufts University School of Medicine to leverage existing DNA methylation data to better understand the biological pathways linking obesity and increased risk of 13 obesity-related cancers. The research aims to identify specific adiposity-related DNA methylation markers associated with these obesity-related cancers, explore their underlying gene ontology, and...
The National Cancer Institute (NCI) awarded a $162,486 Project Grant under the Cancer Research Manpower (CFDA 93.398) federal grant program to the University of Pittsburgh. The project aims to investigate the functional consequences of high glucose culture on adoptive T cell therapies for cancer. Specifically, the research will (1) identify cellular proteins that are differentially O-GlcNAcylated under high glucose conditions and determine if inhibiting O-GlcNAcylation can restore T cell...