The impact of biologic aging on immunity-related cervical cancer outcome disparities among women living with HIV in zambia

Active Project Grant Awarded Last action

Award ID
R01CA284623
Recipient
Awarding agency
Obligated
$2,188,094

Award facts

Assistance listing
93.395 Cancer Treatment Research
Completion date 63% complete
Place of performance
Houston, TX 77030, USA

Award details come from USAspending.gov.

Description

Abstract
Cervical cancer disproportionately affects women of color from low-socioeconomic geographical locations. Locations, such as sub-saharan africa, can also have a high incidence of human immunodeficiency virus (HIV) infection, and access to cervical cancer screening is generally limited for women living in these underserved communities. Furthermore, people living with human immunodeficiency virus (plwh) have evidence of premature aging, which could contribute to cervical cancer progression and responses to chemoradiation therapy (CRT). CRT is the standard of care for locally advanced cervical cancer, and older women (=52 years of age) treated with CRT have worse side effects than younger (

Transactions

Action Obligated Date
Amendment -$41,677
Amendment $69,565
Amendment $69,565
Amendment $663,373
Amendment $760,825
Original award $666,443

Subawards

Subrecipient Amount Awarded
Tropical Gastroenterology And Nutrition LIMITED Dr Kayamba’s lab will process the serum and peripheral blood mononuclear cells being collected as part of this study. In conjunction with the study team at MD… $27,888
Clinical And Radiation Oncology Society Of Zambia For this R01 proposal, Dr Msadabwe will be multi-PI on this grant. Cancer Diseases hospital will be the lead site for data collection and patient enrollment… $69,565
H. Lee Moffitt Cancer Center And Research Institute Hospital, Inc. The Moffitt Cancer Center team will receive blood samples from patients with a pre-existing diagnosis of HIV and cervical cancer from Zambia. Associated… $323,472
Tropical Gastroenterology And Nutrition LIMITED Dr Kelly’s lab will process the serum and peripheral blood mononuclear cells being collected as part of this study. In conjunction with the study team at… $135,951
University Of Zambia For this R01 proposal, Dr Msadabwe will be multi-PI on this grant. Cancer Diseases hospital will be the lead site for data collection and patient enrollment… $146,108
H. Lee Moffitt Cancer Center And Research Institute Hospital, Inc. The Moffitt Cancer Center team will receive blood samples from patients with a pre-existing diagnosis of HIV and cervical cancer from Zambia. Associated… $323,472

Quick answers

Who received award R01CA284623?

R01CA284623 was awarded to The Univeristy Of Texas M.d. Anderson Cancer Center by National Cancer Institute (National Institutes of Health) on September 19, 2023.

How much is award R01CA284623 worth?

$2,188,094 has been obligated on R01CA284623.

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