Actions for collaborative community engaged strategies for HPV (access HPV)
Active Project Grant Awarded Last action
- Award ID
- R01CA271033
- Recipient
-
The Washington University UEI L6NFUM28LQM5
- Awarding agency
-
National Cancer Institute
National Institutes of Health, Department of Health and Human Services
- Obligated
- $4,460,130
Award facts
- Assistance listing
- 93.393 Cancer Cause and Prevention Research
- Completion date 83% complete
- Place of performance
- St. Louis, MO 63110, USA
Award details come from USAspending.gov.
Description
- Abstract
- Cervical cancer is a major cause of morbidity and mortality in many sub-saharan countries, including nigeria. Expanding human papillomavirus (HPV) vaccination for young girls/women, ages 9-26 years (primary prevention) and HPV self-collection for cervical cancer screening for older women, ages 30-49 (secondary prevention) are both critical to achieving who and nigerian goals for reducing the cervical cancer burden. The nigerian government now recommends HPV vaccination and self-collection, yet uptake is poor. As such, context-specific, targeted and culturally relevant implementation strategies are needed. We focus on HPV vaccination among girls and self-collection among women because of the substantial burden of cervical cancer. Mother-daughter relationships in nigeria can be leveraged to increase HPV vaccination uptake among young girls and HPV self-collection among mothers. Mothers (or similar female caregivers) profoundly influence decisions and preferences about young girls' vaccine uptake in the nigerian cultural context. At the same time, maternal choices about HPV self-collection can be reinforced in discussions with their daughters. In the proposed study, actions for collaborative community-engaged strategies for HPV (ACCESS-HPV), we will use participatory crowdsourcing methods to drive HPV prevention among mother-daughter dyads. Crowdsourcing open calls will allow US to identify locally relevant messages and dissemination techniques to increase uptake of HPV prevention. Then, participatory learning communities will build capacity for community- led implementation of selected strategies. Informed by social learning theory and the pen-3 cultural model, our multi-disciplinary research team proposes the following specific aims: (1) to develop a new combined campaign to increase HPV vaccination for young girls (ages 9-26) and HPV self-collection for mothers (ages 30-49) using crowdsourcing open calls and participatory learning communities; (2) to determine the effectiveness of a final combined campaign on uptake of HPV vaccination among young girls/women and HPV self-collection among their mothers using a stepped-wedge randomized controlled trial; (3) to estimate the impact and cost-effectiveness of the crowdsourced campaign. Our primary outcome will be vaccine uptake (ascertained by clinic records of vaccine uptake) among young girls and HPV self-collection (ascertained by laboratory receipt of specimens) among their mothers. The strong support of the nigerian institute for medical research (NIMR) alongside national HPV programs creates a rich research infrastructure and increases the likelihood of successful implementation. Our multi-disciplinary research team has experience organizing implementation research focused on crowdsourcing and community participation in nigeria. This study will enhance our understanding of HPV prevention in resource-constrained settings. This grant application directly responds to strategic priorities of the united states government, the national institutes of health, the national cancer institute, and not-CA-20-025.
Transactions
| Action | Obligated | Date |
|---|---|---|
| Amendment | $411,040 | |
| Amendment | $112,361 | |
| Amendment | $112,361 | |
| Amendment | $367,361 | |
| Amendment | $367,361 | |
| Amendment | -$97,804 | |
| Amendment | $97,805 | |
| Amendment | -$1 | |
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| Amendment | $460,496 | |
| Amendment | $460,496 | |
| Amendment | -$517,440 | |
| Amendment | $517,440 | |
| Amendment | -$517,440 | |
| Amendment | $517,440 | |
| Amendment | -$517,440 | |
| Amendment | $517,440 | |
| Amendment | $517,441 | |
| Amendment | $517,441 | |
| Amendment | $0 | |
| Amendment | $0 | |
| Amendment | $0 | |
| Amendment | $0 | |
| Amendment | $566,886 | |
| Original award | $566,886 |
Show all 26
Subawards
| Subrecipient | Amount | Awarded |
|---|---|---|
| University Of North Carolina At Chapel Hill | $77,750 | |
| Saint Louis University | $38,837 | |
| Nigerian Institute Of Medical Research | $112,361 | |
| Wake Forest University Health Sciences | $45,000 | |
| Nigerian Institute Of Medical Research | $89,808 |
Quick answers
Who received award R01CA271033?
R01CA271033 was awarded to The Washington University by National Cancer Institute (National Institutes of Health) on September 22, 2022.
How much is award R01CA271033 worth?
$4,460,130 has been obligated on R01CA271033.
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