Phone enabled implementation of cessation support (phoenics)

Active Project Grant Awarded Last action

Award ID
R01CA262319
Recipient
Awarding agency
Obligated
$4,452,413

Award facts

Assistance listing
93.393 Cancer Cause and Prevention Research
Completion date 83% complete
Place of performance
Gainesville, FL 32611, USA

Award details come from USAspending.gov.

Description

As the agency reported it.

Abstract
The objective of this proposal is to evaluate the comparative effectiveness of promising multi-component interventions for implementing evidence-based tobacco treatment in lebanon's national system of safety net primary healthcare centers, which serves more than 50% of the population. This objective is directly responsive to NCI notice of special interest (not-CA-20-025): dissemination and implementation science for cancer prevention and control in low resource environments. The tobacco use burden in lebanon is exceptionally high: 35% of adults are current cigarette smokers, 39% are waterpipe smokers, and 5% are dual smokers. The who endorses three interventions as the standard of practice for population-level tobacco dependence treatment: smoking cessation advice integrated into primary care settings; easily-accessible phone-based counseling; and low-cost nicotine replacement therapy (NRT). However, the evidence for these interventions comes primarily from high-income countries and they have rarely been evaluated in low- and middle-income countries (lmics). Further, recommended interventions are not integrated as a routine part of primary care in lebanon, as is the case in other low-resource settings. Addressing this evidence-to-practice GAP requires research on multilevel interventions and contextual factors for implementing integrated, scalable, and sustainable cessation treatment within low-resource settings. We will conduct a group-randomized trial comparing three arms: 1) ask about tobacco use, advise to quit, assist with brief counseling (AAA) as standard care; 2) ask, advise, connect to phone-based counseling (AAC); and 3) AAC+NRT. Our central hypothesis is that connecting patients to phone-based counseling with NRT is the most effective alternative. Our hybrid design is informed by the exploration, preparation, implementation, sustainment (epis) framework which emphasizes key steps and multilevel factors to optimize implementation success. We will pursue the following specific aims: 1) adapt and tailor an existing smoking cessation program to deliver phone-based counseling to smokers in lebanon; 2) test the effectiveness and cost-effectiveness of a referral-based program that delivers smoking cessation services to primary care patients; and 3) identify the multilevel determinants of implementation and sustainability using mixed methods. The proposed project addresses the evidence-to- practice GAP in the provision of tobacco dependence treatment within low-resource settings by developing and testing contextually-tailored multilevel interventions and optimizing implementation success and sustainability. This research is significant for its potential to guide the large-scale adoption of cost-effective strategies for implementing tobacco dependence treatment in low-resource settings thereby reducing tobacco-related morbidity and mortality.

Transactions

Action Obligated Date
Amendment $202,069
Amendment $399,717
Amendment $202,069
Amendment $310,456
Amendment $166,242
Amendment $493,707
Amendment $493,707
Amendment $524,696
Amendment $524,696
Amendment $567,527
Original award $567,527
Show all 11

Subawards

Subrecipient Amount Awarded
George Mason University Dr. Nakkash, along with Dr. Salloum, will be responsible for the principal scientific and managerial oversight of the project. She will supervise the project… $45,614
New York University Dr. Shelley will attend regular research team meetings, support the development of study assessment tools and participate in adapting intervention materials and… $21,481
American University Of Beirut Dr. Kabakian-Khasholian will supervise the project staff at AUB, will oversee all research activities in Lebanon, and will work closely with Dr. Salloum and the… $202,069
New York University Dr. Shelley will attend regular research team meetings, support the development of interview guides, and contribute to the curriculum and planning of the… $23,400
George Mason University Dr. Nakkash, along with Dr. Salloum, will be responsible for the principal scientific and managerial oversight of the project. She will supervise the project… $48,513
New York University Dr. Shelley will attend regular research team meetings, support the development of study assessment tools and participate in adapting intervention materials and… $63,303
American University Of Beirut Dr. El-Jardali will supervise the project staff at AUB, will oversee all research activities in Lebanon, and will work closely with Dr. Salloum and the… $576,641
New York University Dr. Shelley will attend regular research team meetings, support the development of study assessment tools and participate in adapting intervention materials and… $21,147

Quick answers

Who received award R01CA262319?

R01CA262319 was awarded to University Of Florida by National Cancer Institute (National Institutes of Health) on September 9, 2022.

How much is award R01CA262319 worth?

$4,452,413 has been obligated on R01CA262319.

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