Adaptation and implementation of a patient navigation program for cervical cancer screening across contexts in senegal

Active Project Grant Awarded Last action

Award ID
R01CA258683
Recipient
Awarding agency
Obligated
$5,555,269

Award facts

Assistance listing
93.393 Cancer Cause and Prevention Research
Completion date 91% complete
Place of performance
Chicago, IL 60612, USA

Award details come from USAspending.gov.

Description

Abstract
Abstract cervical cancer mortality is expected to increase by 42% to 442,926 deaths worldwide by 2030. Currently 85% of incident cervical cancers and 87% of cervical cancer deaths occur in low- and middle-income countries (lmic). Due in large part to the low utilization of cervical cancer screening services, senegal ranks 17TH in the world for cervical cancer incidence. For women ages 40 to 49 in rural regions of the country the cervical cancer screening rate is very low at less than 2%. As a result women often present with mostly preventable late stage cancers. Secondary prevention programs (cervical cancer screening) are critical to effectively achieving global progress toward the elimination of human papillomavirus related cancers. However, considerable context variation across geographic- and health system-levels in lmics markedly obstructs the community responsiveness of an implemented program. Lessons learned from higher resource countries show that incidence and mortality rates decline and early deaths are prevented with early detection and appropriate follow- up and treatment. Prior efforts and pilot studies in senegal show that there is slow uptake, poor follow-up, and low treatment rates for women who are screened positive. Patient navigation is a strategy to eliminate barriers to screening, timely diagnosis, and follow-up to improve cancer outcomes in vulnerable populations. In high-income countries, patient navigation has demonstrated considerable effectiveness in its ability to address communication, information, medical system, and emotional barriers to timely care across all phases of the cancer care continuum, including detection, diagnosis, treatment, and post-treatment quality of life. Patient navigation programs enhance access to care, promote self-efficacy, and sustain patient engagement with care, and have been shown to improve cancer outcomes, particularly among marginalized groups, rural populations, and impoverished communities. The goal of this project is to prevent unnecessary deaths due to cervical cancer in senegal. This mixed methods research responds to identified intrapersonal- and community-level barriers to early cervical cancer screening uptake, follow-up, and treatment among women there. We will apply the dynamic adaptation process to study the adaptation of an evidence-based cervical cancer patient navigation program in urban and rural contexts of senegal, measure the intervention effectiveness, and evaluate programmatic implementation outcomes. By studying the process of adaptation of a patient navigation program in a low- and middle-income country, we will apply implementation science to a novel context. With a particular focus on how the adaptation responds to cancer-related stigma and women's autonomy in healthcare decision-making, our project demonstrates additional innovation. The process knowledge generated will further our long-term goal to inform the national cervical cancer prevention and control programs in senegal and other low- and middle-income countries.

Transactions

Action Obligated Date
Amendment $0
Amendment $281,178
Amendment $281,178
Amendment $408,122
Amendment $408,122
Amendment $408,122
Amendment $281,178
Amendment -$220,901
Amendment $542,495
Amendment $542,495
Amendment -$5,974
Amendment -$5,974
Amendment $173,587
Amendment $173,587
Amendment $173,587
Amendment $519,467
Amendment $519,467
Amendment $519,467
Original award $556,066
Show all 19

Subawards

Subrecipient Amount Awarded
Universitã? Cheikh Anta Diop De Dakar Adama Faye, M.D., M.P.H., Ph.D., Principal Investigator in Senegal and for UCAD Subcontract: 30% effort (3.6 person months) in Year 4, $11,500 Pr. Faye is a MPI… $281,178

Quick answers

Who received award R01CA258683?

R01CA258683 was awarded to University Of Illinois by National Cancer Institute (National Institutes of Health) on April 1, 2022.

How much is award R01CA258683 worth?

$5,555,269 has been obligated on R01CA258683.

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