Project Grant R01AT013779
- The National Science Foundation awarded North Carolina Agricultural and Technical State University $549,484 on October 1, 2025, under the Computer and Information Science and Engineering program (CFDA 47.070) to develop and demonstrate a noninvasive, direct bidirectional brain-to-brain interface (B2BI) combining electroencephalography-based motor-imagery brain-computer interface (EEG-MI BCI) technology with transcranial focused ultrasound (tFUS) computer-brain interface (CBI) capability in human...
- The National Institute of Mental Health awarded the University of California, Los Angeles $424,433 on March 1, 2026, under the Mental Health Research Grants program (CFDA 93.242) to develop a framework and online implementation tool for participant engagement in brain-computer interface early feasibility studies. The project addresses a critical gap in BCI research: while participant engagement is recognized as valuable in other clinical domains, BCI early feasibility studies—where people with...
- The National Science Foundation Division of Information and Intelligent Systems awarded the University of Maryland Baltimore County $265,140 on October 1, 2025, under the Computer and Information Science and Engineering program (CFDA 47.070) to develop fully wireless flexible electrical-acoustic implants for high-resolution neural stimulation and recording at large scale. The project advances minimally invasive ultrasound neuromodulation and neural recording of the brain with high spatial...
- The National Center for Complementary and Integrative Health, part of the Department of Health and Human Services National Institutes of Health, awarded $398,970 to the University of Alabama at Birmingham on August 15, 2026, under the Research and Training in Complementary and Integrative Health program (CFDA 93.213). The award funds development of soft wearable electronic skin sensors to quantify real-time complex force dynamics during force-based manipulation and manual therapy. The soft...
- The National Science Foundation Division of Computing and Communication Foundations awarded $700,000 to Trustees of Tufts College on October 1, 2026, under the Computer and Information Science and Engineering program (CFDA 47.070) to advance non-invasive brain-computer interfaces using functional near-infrared spectroscopy. The project develops improved hardware, software, and mathematical techniques to distinguish between task-positive and default-mode networks in the prefrontal...
- The National Institute of Neurological Disorders and Stroke awarded the University of Kansas Medical Center Research Institute $580,517 on September 3, 2026, to examine neural features that improve brain-computer interface precision and reliability under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The recipient will conduct three experiments to improve BCI decoders that translate neural signals into reaching and grasping when task...
- The National Science Foundation Division of Electrical, Communications and Cyber Systems awarded the University of Maryland Baltimore County $121,578 on October 1, 2025, for research on minimally invasive implantable microscopic ultrasound neuromodulation under the CAREER program (CFDA 47.041, Engineering). The project develops ultrasound-based neuromodulation technology designed to achieve microscopic spatial resolution (hundreds of micrometers and below) with whole-brain coverage while...
- The National Center for Complementary and Integrative Health (NCCIH), a component of the Department of Health and Human Services National Institutes of Health, awarded $407,856 to Cleveland Clinic Lerner College of Medicine of Case Western Reserve University on August 1, 2026, under the Research and Training in Complementary and Integrative Health program (CFDA 93.213). The recipient will conduct research examining how alpha-frequency transcranial alternating current stimulation (tACS) targeting...
- The National Institute of Biomedical Imaging and Bioengineering awarded the University of Pittsburgh $235,550 on August 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop programmable ultrasound-leveraged site-specific exosomes for precise therapeutic delivery to the brain. The project addresses spatial and temporal control of drug delivery in neurological disorders by engineering exosomes—biocompatible...
- The National Institute of Biomedical Imaging and Bioengineering awarded the University of North Carolina at Chapel Hill $570,612 on April 7, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop advanced volumetric ultrasound systems for functional imaging and multi-targeted closed-loop neuromodulation. The project addresses current limitations in ultrasonic neuromodulation by moving beyond MRI-dependent targeting...
The National Center for Complementary and Integrative Health awarded Carnegie Mellon University $616,764 on September 1, 2026, under the Research and Training in Complementary and Integrative Health program (CFDA 93.213) to develop and investigate a bidirectional brain-computer interface (BI-BCI) platform combining electroencephalography-based neural decoding with closed-loop transcranial focused ultrasound neuromodulation. The award funds two specific research aims. Aim 1 establishes a transcranial focused ultrasound-integrated motion-onset visual evoked potential BCI speller for communication, investigating neural mechanisms of cognitive attention during mind-body interactions by enhancing feature-based attention mechanisms through motion-onset visual stimulation combined with targeted neuromodulation of visual area V5. Aim 2 develops and investigates a transcranial focused ultrasound-modulated sensorimotor rhythm BI-BCI using motor imagery for motor control, testing whether transcranial focused ultrasound modulates event-related sensorimotor dynamics. The dual approach enables real-time measurement of behavior via BCI decoding and adaptive modulation of neural circuits, offering a platform for mechanistic studies of mind-body interventions. Work is performed in Pittsburgh, Pennsylvania. The period of performance extends through June 30, 2031.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $616.8k | 9/3/26 |