Project Grant R01AT006330

The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $3,565,780 Project Grant under the Drug Use and Addiction Research Programs (CFDA 93.279) to The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), to develop a groundbreaking high frequency trans-spinal magnetic stimulation (HF-TSMS) system for the non-invasive treatment of neuropathic pain. The project aims to refine the HF-TSMS technology to target neural pathways involved in...

The U.S. National Institute of Neurological Disorders and Stroke (NINDS) awarded a $1,643,228 Cooperative Agreement grant under the Drug Abuse and Addiction Research Programs (CFDA 93.279) to Worcester Polytechnic Institute (WPI) to develop an Integrative Mindfulness-Based Predictive Approach for Chronic Low Back Pain Treatment (IMPACT). The key objectives of this 2-year IMPACT project are to: 1) Initiate a clinical trial of Mindfulness-Based Stress Reduction (MBSR) for chronic low back pain...

The University of Utah Office of Sponsored Projects Division was awarded a $423,500 Project Grant under the National Institutes of Health's "Research and Training in Complementary and Integrative Health" (CFDA 93.213) program. The grant will fund a two-arm, randomized, masked study investigating the effects of Swedish Massage Therapy (SMT) versus a Light Touch control on brain activity in subjects with Generalized Anxiety Disorder (GAD). The primary objectives are to identify brain...

This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Drug Use and Addiction Research Programs (CFDA 93.279), provides $1,325,500 to develop novel PAC1 receptor antagonists for the treatment of medication overuse headache (MOH). The project aims to leverage a collaborative research effort between the Pradhan, Katritch, and Majumdar labs to identify and characterize promising lead compounds targeting the PAC1 receptor, which plays a key...

This federal Project Grant award, valued at $1,339,480.00 and awarded on September 30, 2024, was provided by the Department of the Army Medical Command under the Military Medical Research and Development (CFDA 12.420) program. The grant supports research to develop and evaluate the efficacy of a novel, patient-centered physical therapy intervention called SPINEPASS for the treatment of persistent headache following mild traumatic brain injury. The key objectives are to: Establish the efficacy of...

This $14.2 million project grant from the National Institute of Neurological Disorders and Stroke, part of the Department of Health and Human Services, will fund research from September 2022 to August 2025 under the Drug Abuse and Addiction Research Programs (CFDA 93.279). The Massachusetts General Hospital will investigate the mechanisms by which spinal cord stimulation reduces pain, with the goal of improving device design and patient selection. Researchers will apply specialized nerve...

The National Institutes of Health National Institute of Neurological Disorders and Stroke awarded an $11.2 million project grant to the University of Pittsburgh to define the mechanisms of pain relief associated with dorsal root ganglion and spinal cord stimulation. This three-year grant will support research under the Drug Abuse and Addiction Research Programs (CFDA 93.279) to advance understanding of neuromodulatory devices for chronic pain treatment. The University will conduct preclinical...

The National Institutes of Health National Center for Complementary and Integrative Health awarded New York University $785,637 under the Research and Training in Complementary and Integrative Health program (CFDA 93.213) from June 2021 through May 2025. This Cooperative Agreement will support the development and pilot testing of telephone-delivered and video-based Mindfulness-Based Cognitive Therapy (MBCT) protocols for patients with migraine headaches and depressive symptoms. Specifically, the...

The National Center for Complementary and Integrative Health (NCCIH) awarded a $817,330 Project Grant (CFDA 93.213 - Research and Training in Complementary and Integrative Health) to the Rector & Visitors of the University of Virginia (UVA) to evaluate an adaptive intervention to improve pain outcomes following cognitive behavioral therapy for insomnia in patients with comorbid chronic low back pain and insomnia. The project aims to determine if adding a positive affect enhancing...

This $4.7 million project grant from the National Institutes of Health's National Institute of Neurological Disorders and Stroke will support the development of electrophysiological and ultrasound quantitative biomarkers for myofascial pain syndrome. The grant to Beth Israel Deaconess Medical Center will establish the use of electrical impedance myography, myofiber threshold tracking excitability testing, and ultrasound shear wave elastography to assess differences between patients with active...