Project Grant R01AI198258
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of New South Wales a Project Grant totaling $147,822 on June 22, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855), with a completion date of May 31, 2028. This award funds research investigating the role of NUP358/RANBP2 nucleoporin as a molecular adaptor facilitating microtubule-based transport of HIV (human immunodeficiency virus) capsids...
- Federal Project Grant Award Summary Griffith University received a $549,032 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded September 10, 2025, with a completion date of August 31, 2028. The grant funds research and development of a biopolymer particle-based multistage malaria vaccine platform designed to provide ambient-temperature stability and cost-effective mass production...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Southern California $835,021 on July 7, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to characterize trained innate immunity mediated by a novel immunomodulatory mixture. The research focuses on developing and optimizing a protein-free combination of aluminum hydroxide, monophosphoryl lipid, and fungal mannan to prevent hospital-acquired...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Applied Biomedical Science Institute a Project Grant of $976,318 under the Allergy and Infectious Diseases Research program (CFDA 93.855) on April 6, 2026, with completion targeted for March 31, 2031. The award funds research to elucidate the molecular mechanisms underlying ultralong complementarity-determining region H3 (CDR H3) antibodies produced by cattle. The Institute will...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Johns Hopkins University a Project Grant of $766,437 on June 1, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855). This five-year award, with an ultimate completion date of May 31, 2031, supports research to define the vaccine-induced B cell responses, T cell responses, and innate immune responses associated with protection against dengue virus (DENV)...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded University of California Irvine $721,365 under the Allergy and Infectious Diseases Research program (CFDA 93.855) for a Project Grant beginning April 1, 2026, and concluding March 31, 2031. The award funds research to develop an optimized nanoparticle-hydrogel vaccine platform designed to enhance immune response breadth against influenza, particularly H5N1 avian influenza. The research employs a...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Scripps Research Institute a Project Grant of $931,385 under the Allergy and Infectious Diseases Research program (CFDA 93.855) on June 10, 2026, with a completion date of May 31, 2027. The award supports research and development of glycoengineered HIV-1 envelope vaccine immunogens designed to enhance neutralizing antibody responses. The primary deliverable involves producing core...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a Project Grant of $454,278 to The University of Kentucky Research Foundation on August 15, 2025, under the Allergy and Infectious Diseases Research program (CFDA 93.855). The project, entitled "Adjuvanted Intranasal Influenza Vaccine to Generate Lung Resident-Memory T Cells," will develop and evaluate a novel influenza vaccine formulation designed to provide broadly cross-reactive and...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Scripps Research Institute a Project Grant totaling $1,285,304 under the Allergy and Infectious Diseases Research program (CFDA 93.855) to develop and evaluate an enhanced HIV vaccine regimen capable of producing durable broadly neutralizing antibody (BNAB) responses. The research, which commenced August 1, 2025, and extends through July 31, 2030, leverages a novel six-shot germline-targeting...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Johns Hopkins University a Project Grant totaling $100,228 under the Allergy and Infectious Diseases Research program (CFDA 93.855) for research on extrafollicular memory B cell responses during influenza infection. The award, effective November 27, 2026, with completion targeted for June 30, 2029, supports research conducted at the Johns Hopkins University facility in Baltimore, Maryland....
The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Sydney $736,873 through the Allergy and Infectious Diseases Research program (CFDA 93.855) via Project Grant mechanism, effective July 10, 2026, with completion targeted for June 30, 2031. This research award supports detailed investigations into the mechanism of action (MOA) of the MPL-QS21 adjuvant combination—specifically monophosphoryl lipid A (MPL), a toll-like receptor 4 agonist, and QS21, a saponin—when formulated in cholesterol-containing liposomes as AS01. The research encompasses both human and murine studies designed to elucidate how these adjuvants work independently and synergistically to enhance immune responses to vaccine antigens, with particular focus on understanding innate and adaptive immune cell interactions within lymph node tissue. The deliverables include scientific data and analysis clarifying adjuvant mechanisms that drive polyfunctional CD4 T cell responses and durable neutralizing antibody production, with direct application to optimizing future vaccine design—particularly for protein-based recombinant vaccines similar to recombinant zoster vaccine (Shingrix) and adjuvanted influenza vaccine (Fluad). By advancing mechanistic understanding of combination adjuvants, this research addresses the unmet medical challenge of matching adjuvants to vaccine antigens, thereby reducing developmental timelines and costs during pre-clinical and clinical vaccine translation while maintaining safety profiles.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $736.9k | 7/10/26 |