Project Grant R01AI195818
- Federal Grant Award Summary Yale University received a $192,364 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective August 4, 2025, through July 31, 2030. The award supports investigator-initiated research examining how antimalarial drugs administered to human populations affect parasite development and drug resistance selection within mosquito vectors. The research will...
- Federal Project Grant Award Summary Yale University received a $131,995 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective August 13, 2025, with a completion date of July 31, 2029. The award funds research investigating the olfactory responses of tsetse flies to trypanosome-induced volatile compounds, addressing a critical public health challenge affecting 70 million people...
- Federal Project Grant Award Summary Yale University received a $3.26 million Project Grant from the National Institute of Allergy and Infectious Diseases under the Allergy and Infectious Diseases Research program (CFDA 93.855) for the period August 1, 2025, through July 31, 2029. The award funds research to elucidate molecular mechanisms of Mycobacterium tuberculosis (MTB) cell envelope assembly, with the goal of identifying drug synergy opportunities to enhance antibiotic efficacy. The...
- Federal Grant Award Summary Yale University received a $837,497 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective May 6, 2025, through April 30, 2030. The grant funds basic science research focused on elucidating the molecular mechanisms by which phosphoinositide 3-kinase gamma (PI3KG) orchestrates antibody responses in B cells. The research deliverables encompass three...
- Federal Grant Award Summary Yale University received a $2,543,522 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded September 3, 2025, with completion targeted for August 31, 2029. The award funds investigator-initiated biomedical research examining novel mechanisms of protein homeostasis mediated by the molecular chaperone DnaK in bacterial cells. This research addresses...
- Federal Grant Award Summary Yale University received a $453,629 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded July 8, 2025, with completion targeted for June 30, 2027. The grant supports development and application of PHAGE-SEQ, a high-throughput technology combining phage display of nanobodies (VHH recognition domains derived from camelid heavy chain-only immunoglobulins)...
- Federal Grant Award Summary Yale University received a $735,631 Project Grant from the National Institute of Allergy and Infectious Diseases under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective April 1, 2026, through March 31, 2031. The award funds basic immunological research investigating the origin, function, and biological properties of a novel population of CX3CR1+ neutrophils—specialized white blood cells distinct from canonical neutrophils. The research...
- Federal Grant Award Summary Brown University received a $791,611 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded on April 10, 2026, with a completion date of March 31, 2031. The project focuses on the discovery and development of novel antimalarial drugs targeting Plasmodium falciparum GRP (PfGARP) for parenteral therapy treatment of severe falciparum malaria. This research...
- Federal Grant Award Summary Yale University received a $603,338 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective July 3, 2025, with a completion date of June 30, 2030. The award supports advanced structural and computational research investigating human immunodeficiency virus 1 (HIV-1) fusion mechanisms on native cell membranes. The primary deliverables include...
- Federal Project Grant Award Summary Yale University received a $461,250 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded July 10, 2025, with a completion date of June 30, 2027. The project delivers research services focused on single-cell phenotyping methodologies to advance tuberculosis (TB) drug discovery. The research team will identify subcellular environments associated with...
Federal Grant Award Summary Yale University received a $580,306 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective April 13, 2026 through March 31, 2031. The award funds research addressing residual malaria transmission in the Peruvian Amazon, particularly in the Loreto region, which accounts for approximately 95% of malaria cases in Peru and 25% of all malaria cases in the Americas. The research project aims to decipher mechanisms underlying persistent malaria transmission despite current control interventions and to inform development of novel, effective control strategies. The deliverables under this grant include characterization of sociodemographic, behavioral, environmental, and genetic factors contributing to individual malaria risk and reinfection; identification of risk profiles in residual malaria populations; network analysis examining parasite transmission interconnectedness between remote and proximal sites; and tracking of malaria transmission trends and hotspot identification in remote indigenous populations through field-deployable molecular diagnostics. These research activities will generate scientific knowledge to support Peru's malaria elimination goals and advance understanding of residual transmission mechanisms in challenging endemic settings.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $580.3k | 4/13/26 |