Project Grant R01AI192916
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded University of Maryland, Baltimore a $463,676 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective August 7, 2025, with completion targeted for July 31, 2030. This research initiative will generate scientific knowledge and methodological advances focused on understanding Fc-mediated effector functions in infectious disease contexts, specifically...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $678,218 Project Grant to the University of Maryland, Baltimore, effective April 1, 2026, through March 31, 2031, under the Allergy and Infectious Diseases Research program (CFDA 93.855). This award supports multi-omics research investigating bacterial-host interactions between the filarial nematode Brugia malayi and its obligate Wolbachia bacterial endosymbiont. The research...
- Federal Project Grant Award Summary Duke University's Office of Research Administration is conducting a five-year research initiative funded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). This $829,735 project, which commenced April 1, 2026 and extends through March 31, 2031, focuses on the discovery and optimization of broadly protective neutralizing antibodies against MERS-related betacoroviruses...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded University of Maryland, Baltimore $136,988 under the Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct investigator-initiated biomedical research on Enterovirus D68 (EV-D68) infection mechanisms. The award, obligated on August 20, 2025, with a project completion date of July 31, 2027, supports research designed to advance scientific understanding of how transcription...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Maryland, College Park $1.795 million under the Allergy and Infectious Diseases Research program (CFDA 93.855) for a four-year project period (August 1, 2025 – July 31, 2029). The award supports development of a Phenotypically Amplified Beta-Lactamase (PHABL) assay, a rapid diagnostic tool designed to identify beta-lactam-resistant bacterial pathogens in bloodstream...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Maryland, College Park a $749,353 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective April 1, 2026, through March 31, 2031. This award funds investigator-initiated biomedical research to elucidate the cellular and molecular mechanisms of Cryptococcal Immune Reconstitution Inflammatory Syndrome (IRIS), a life-threatening condition...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $455,500 Project Grant to the University of Maryland, Baltimore under the Allergy and Infectious Diseases Research program (CFDA 93.855) on February 3, 2026, with a completion date of January 31, 2028. This award supports investigator-initiated research to characterize cord-blood-specific gamma-delta T cells and elucidate their functional heterogeneity in neonates and infants. The research...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Maryland, Baltimore $445,488 under the Allergy and Infectious Diseases Research program (CFDA 93.855) for a two-year project period from July 1, 2025 through June 30, 2027. This Project Grant supports scientific research to characterize long non-coding RNAs (lncRNAs) in Plasmodium falciparum and elucidate their roles in gene regulation. The research deliverables include...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Maryland, College Park $421,720 under the Allergy and Infectious Diseases Research program (CFDA 93.855) on February 2, 2026, with a completion date of January 31, 2028. This Project Grant supports basic research characterizing the activation of NLRP11 (nucleotide-binding oligomerization domain-like receptor family pyrin domain-containing 11) inflammasome by mycobacterial...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $899,935 to the Scripps Research Institute under the Allergy and Infectious Diseases Research program (CFDA 93.855) on June 10, 2025, to identify novel B cell epitopes against human coronaviruses. The research will utilize an integrated platform combining comprehensive characterization, high-resolution structural determination, state-of-the-art multi-bait B cell isolation strategies, and...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Maryland, Baltimore $896,045 on May 6, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to develop broadly-protective immunotherapeutic molecules targeting coronavirus vulnerabilities. The project, which extends through April 30, 2031, focuses on identifying pan-coronavirus epitopes through shark-derived Variable New Antigen Receptor (VNAR) nanobody repertoires. Researchers will interrogate nanobody libraries generated from nurse sharks sequentially immunized with heterologous coronavirus spike protein fragments, including SARS-CoV-2, SARS-CoV-1, MERS-CoV, and 229E, to identify conserved neutralizing epitopes that can be targeted for therapeutic intervention. The deliverables include recombinant nanobody production and comprehensive functional characterization through binding affinity assays, competition mapping studies, pseudovirus and live-viral neutralization assays, and in vivo protection studies using animal models that replicate high-risk human populations. The project aims to identify VNAR nanobodies capable of targeting pan-sarbecovirus and pan-merbecovirus epitopes, among other coronavirus lineages, with the ultimate goal of developing readily deployable immunotherapeutic candidates for rapid deployment in response to future coronavirus spillover events with pandemic potential.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $896.0k | 5/6/26 |