Project Grant R01AI192648
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $684,627 Project Grant under the Allergy and Infectious Diseases Research Program (CFDA 93.855) to Georgia State University Research Foundation Inc. to investigate the interactions between the sexually transmitted pathogen Neisseria gonorrhoeae (the cause of gonorrhea) and host cell glycans. The research aims to understand how the pathogen's conserved outer membrane transport proteins bind to human glycans, potentially...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $4,362,124 Cooperative Agreement on August 12, 2025 under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855) to The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. The purpose of this award is to advance the development of a promising vaccine candidate against gonorrhea through preclinical testing and into clinical trials. The key products and services to be...
- This federal Project Grant award of $243,750 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) supports research to investigate how the bacterium Gardnerella promotes the pathogenesis of Neisseria gonorrhoeae, the causative agent of the sexually-transmitted infection gonorrhea. The key objectives are to determine the mechanisms by which Gardnerella virulence factors, including the cytolytic toxin...
- The University of Georgia Research Foundation, Inc. received a $415,250 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research CFDA program. The grant, awarded on Aug 21, 2025, aims to characterize a feedback signal balancing lipopolysaccharide and glycerophospholipid synthesis in Gram-negative bacteria. The research will develop analytical tools to quantify lipopolysaccharide transport intermediates and...
- This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research Program (CFDA 93.855) provides $837,644 to Michigan State University from November 2024 through October 2029. The primary objectives are to develop comprehensive libraries of synthetic oligosaccharides with varied amine/acetylation patterns of poly-β-(1-6)-N-acetylglucosamine (PNAG) and evaluate their potential as effective anti-microbial vaccine...
- This Project Grant award, valued at $416,276.00 and provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855), aims to investigate factors that modulate the Fc-mediated immune responses of antibodies. The research seeks to increase the potency of protection resulting from antibodies requiring Fc functions for influenza virus or antibodies against Streptococcus pneumoniae. The University...
- This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research (CFDA 93.855) federal grant program, provides funding for research on Neisseria gonorrhoeae, the bacterial pathogen responsible for the sexually transmitted infection gonorrhea. The research focuses on understanding how the pathogen adapts to overcome nutritional immunity, specifically the sequestration of essential iron by the host. The key...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $243,235 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to The Johns Hopkins University. This grant will fund the development and validation of direct-from-sample whole genome sequencing methods for Neisseria gonorrhoeae (NG) to support expanded genomic surveillance of NG and other bacterial sexually transmitted infections in populations with high HIV burdens in Eastern and...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $1,000,000 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to Taxis Pharmaceuticals Inc. for the "Lead Optimization of Oral DHFR Inhibitor for the Treatment of Multidrug-Resistant N. Gonorrhoeae Infections" project. The grant supports the development of a new oral antibiotic to treat gonorrhea infections that have become resistant to existing therapies. The proposed...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $404,539 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to The Rochester General Hospital. The grant will fund the development and evaluation of a novel Haemophilus influenzae lipoprotein fusion vaccine and vaccine platform. Key research objectives include assessing the immunogenicity and protective efficacy of lipidated and fusion protein constructs against nasopharyngeal...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $660,334 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to Georgia State University Research Foundation Inc. to develop an innovative outer membrane vesicle (OMV)-based vaccine for protection against the pathogenic Neisseria gonorrhoeae (NGO), the human-specific bacterium that causes gonorrhea. The grant supports research to generate OMV vaccines expressing binding-defective derivatives of conserved outer membrane transport proteins critical for NGO growth during human infection. These vaccines will be tested in transgenic mouse models expressing human ligands for the transport systems. The goal is to develop a vaccine that elicits a protective immune response against these surface antigens to fully protect against gonococcal infections.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $300.7k | 9/24/25 | ||
| Not listed | $359.6k | 9/23/25 |