Project Grant R01AI184894
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $660,334 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to Georgia State University Research Foundation Inc. to develop an innovative outer membrane vesicle (OMV)-based vaccine for protection against the pathogenic Neisseria gonorrhoeae (NGO), the human-specific bacterium that causes gonorrhea. The grant supports research to generate OMV vaccines expressing binding-defective...
- This federal Project Grant award of $243,750 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) supports research to investigate how the bacterium Gardnerella promotes the pathogenesis of Neisseria gonorrhoeae, the causative agent of the sexually-transmitted infection gonorrhea. The key objectives are to determine the mechanisms by which Gardnerella virulence factors, including the cytolytic toxin...
- This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research (CFDA 93.855) federal grant program, provides funding for research on Neisseria gonorrhoeae, the bacterial pathogen responsible for the sexually transmitted infection gonorrhea. The research focuses on understanding how the pathogen adapts to overcome nutritional immunity, specifically the sequestration of essential iron by the host. The key...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $4,362,124 Cooperative Agreement on August 12, 2025 under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855) to The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. The purpose of this award is to advance the development of a promising vaccine candidate against gonorrhea through preclinical testing and into clinical trials. The key products and services to be...
- The University of Georgia Research Foundation, Inc. received a $415,250 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research CFDA program. The grant, awarded on Aug 21, 2025, aims to characterize a feedback signal balancing lipopolysaccharide and glycerophospholipid synthesis in Gram-negative bacteria. The research will develop analytical tools to quantify lipopolysaccharide transport intermediates and...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $243,235 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to The Johns Hopkins University. This grant will fund the development and validation of direct-from-sample whole genome sequencing methods for Neisseria gonorrhoeae (NG) to support expanded genomic surveillance of NG and other bacterial sexually transmitted infections in populations with high HIV burdens in Eastern and...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $1,000,000 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to Taxis Pharmaceuticals Inc. for the "Lead Optimization of Oral DHFR Inhibitor for the Treatment of Multidrug-Resistant N. Gonorrhoeae Infections" project. The grant supports the development of a new oral antibiotic to treat gonorrhea infections that have become resistant to existing therapies. The proposed...
- This federal Project Grant award, provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research to understand how the menstrual cycle and associated immune changes impact the development of chlamydia and gonorrhea infections in women and adolescent girls. The $2,112,000 grant was awarded to Emory University on September 22, 2025, with a final completion date of August 31, 2029. The...
- This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research Program (CFDA 93.855) provides $837,644 to Michigan State University from November 2024 through October 2029. The primary objectives are to develop comprehensive libraries of synthetic oligosaccharides with varied amine/acetylation patterns of poly-β-(1-6)-N-acetylglucosamine (PNAG) and evaluate their potential as effective anti-microbial vaccine...
- The University of Georgia Research Foundation, Inc. was awarded a $650,020 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The grant, awarded on August 1, 2025, supports research to determine the mechanisms by which memory regulatory T cells (mTregs) provide protection against recurring malaria infections caused by Plasmodium. The research aims to understand how mTregs transition to a T...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $684,627 Project Grant under the Allergy and Infectious Diseases Research Program (CFDA 93.855) to Georgia State University Research Foundation Inc. to investigate the interactions between the sexually transmitted pathogen Neisseria gonorrhoeae (the cause of gonorrhea) and host cell glycans. The research aims to understand how the pathogen's conserved outer membrane transport proteins bind to human glycans, potentially enabling new therapeutic approaches to combat the growing threat of drug-resistant gonorrhea. The award period runs from September 2025 through August 2030, supporting studies to characterize the role of these transporter-glycan interactions in nutrient acquisition and host cell association by the pathogen.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $227.6k | 9/17/25 | ||
| Not listed | $457.0k | 9/15/25 |