This $130,064 federal Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences (CFDA 47.049) program supports collaborative research to develop new statistical algorithms for analyzing spatiotemporal data on vector-borne disease transmission, using dengue virus in Rio de Janeiro as a case study. The project aims to address methodological challenges in modeling complex, nonlinear, and partially-observed spatial-temporal systems, with the goal of...
This National Science Foundation (NSF) Project Grant award, funded under the Social, Behavioral, and Economic Sciences program (CFDA 47.075), aims to investigate the role of human behavior in the dynamics of mosquito-borne diseases such as dengue and Zika. The $100,000 grant, awarded to North Carolina State University (NC State), will support a multidisciplinary research project to understand how individual decision-making around mosquito prevention behaviors impacts disease transmission. The...
This Project Grant award for $323,038 from the National Science Foundation's (NSF) Mathematical and Physical Sciences (CFDA 47.049) program supports a collaborative research project among the University of Miami, Indiana University, and Nova Southeastern University. The project aims to:
Reconstruct the transmission dynamics of chikungunya virus (CHIKV) in Brazil and evaluate control efforts in Florida, integrating mosquito data from Miami-Dade County and local outbreak data.
Assess the...
This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) supports research to understand how human genetic diversity regulates susceptibility and severity of Zika virus infections. The $418,927 award to Duke University aims to 1) identify human genetic variants that confer susceptibility or resistance to cellular Zika virus infection, and 2) experimentally validate the identified genetic variants...
This $570,719 Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) supports research to assess the potential for Mayaro virus (MAYV) to adapt and increase its ability to infect and be transmitted by the urban mosquito species Aedes aegypti and Aedes albopictus. The key objectives are to:
Evaluate the fitness of MAYV after serial passage through Ae. aegypti and Ae. albopictus mosquitoes, as well as...
The National Institute of Allergy and Infectious Diseases (NIAID), under CFDA 93.855 Allergy and Infectious Diseases Research program, awarded a $760,318 Project Grant to the University of California, Davis. The award will fund research to develop recombinant enhanced antiviral sensors (REAVRS) that combine virus-sensing domains with diverse antiviral effector proteins, with the goal of creating broadly-acting antiviral agents. The research will evaluate the antiviral effects of REAVRS in...
This Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) aims to effectively link molecular informatics and network analytics to understand how human mobility contributes to malaria population structure, importation, and diffusion in the northern Peruvian Amazon. The $128,640 award to Duke University supports two key objectives: 1) Collecting primary community network data to quantify human mobility...
This $441,502 Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) supports research to develop novel CRISPR-based genome editing strategies for managing Aedes aegypti mosquito populations that transmit viruses such as yellow fever, Zika, chikungunya, and dengue. The key goals are to design a temperature-dependent CRISPR-Cas12 system that can produce sterile male mosquitoes requiring only a single strain,...
This National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (CFDA 47.049) Project Grant of $246,620 awarded to The University of Texas at San Antonio (UTSA) will fund the development of novel mathematical models for Wolbachia-based strategies to control mosquito-borne diseases like dengue fever, malaria, chikungunya, and Zika. The multi-stage models will account for the complex transmission dynamics, spatial and temporal heterogeneity, and Wolbachia's biological...
This $133,664 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research to characterize the network of vector-host-virus interactions within wetland areas in Argentina. The key objectives are to: 1) identify host bloodmeals in wetland mosquitoes to understand viral flow between resident and migratory birds, 2) analyze previous exposure of birds to St. Louis...