This Project Grant awarded by the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research to characterize host factor changes at the gene and protein level for HIV/hepatitis B virus (HBV) co-infections. The $673,158 award to Emory University will utilize robust co-culture systems of primary human hepatocytes and CD4+ T cells, along with CRISPR screening, proteomics, phosphoproteomics, and secretomics approaches. The goal is to discover and validate host factors and develop potential therapeutics for a functional cure for HBV. The project will run from August 2024 to June 2029.
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