Imaging signatures of early tuberculosis
Active Project Grant Awarded Last action
- Award ID
- R01AI175555
- Recipient
-
Rutgers The State University Of New Jersey UEI YVVTQD8CJC79
- Awarding agency
-
National Institute of Allergy and Infectious Diseases
National Institutes of Health, Department of Health and Human Services
- Obligated
- $3,921,823
Award facts
- Assistance listing
- 93.855 Allergy and Infectious Diseases Research
- Completion date 59% complete
- Place of performance
- Newark, NJ 07107, USA
Award details come from USAspending.gov.
Description
- Abstract
- Early detection of tuberculosis (TB) disease to prevent transmission and disability is hampered by the lack of precise biomarkers to diagnose and predict TB progression. The objective of this study is to develop computational imaging tools to characterize and diagnose individuals without TB symptoms who will progress to sputum culture-positive or symptomatic TB disease. In aim 1, we will combine computed tomography (CT) scans from existing and prospective TB household contact studies to derive a high-resolution radiomic signature to predict and characterize early disease pathology. In aim 2, we will evaluate methods to enhance performance of field-deployable chest-x-RAY computer aided detection (CAD) systems to diagnose early TB using transfer learning, image-to-image training, and integration of clinical and epidemiologic variables. Our goal is to develop a fundamental toolbox for research, diagnosis, and targeted preventive treatment of early TB to prevent transmission and accelerate TB control.
Transactions
| Action | Obligated | Date |
|---|---|---|
| Amendment | $293,858 | |
| Amendment | $361,421 | |
| Amendment | $642,787 | |
| Amendment | $642,787 | |
| Amendment | $65,360 | |
| Amendment | $65,360 | |
| Amendment | $0 | |
| Amendment | $0 | |
| Amendment | $0 | |
| Amendment | $616,750 | |
| Amendment | $616,750 | |
| Original award | $616,750 |
Show all 12
Subawards
| Subrecipient | Amount | Awarded |
|---|---|---|
| Emory University | $31,453 | |
| Makerere University Biomedical Research Centre | $293,858 | |
| University College London | $33,445 | |
| Emory University | $12,582 | |
| Makerere University College Of Health Sciences | $270,010 | |
| University College London | $105,591 | |
| Makerere University College Of Health Sciences | $168,213 | |
| Emory University | $12,520 |
Quick answers
Who received award R01AI175555?
R01AI175555 was awarded to Rutgers The State University Of New Jersey by National Institute of Allergy and Infectious Diseases (National Institutes of Health) on November 9, 2023.
How much is award R01AI175555 worth?
$3,921,823 has been obligated on R01AI175555.
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