Host and parasite factors influencing P. Vivax RBC invasion and asexual development
Active Project Grant Awarded Last action
- Award ID
- R01AI165483
- Recipient
-
University Of Maryland, Baltimore UEI Z9CRZKD42ZT1 Part of University System Of Maryland
- Awarding agency
-
National Institute of Allergy and Infectious Diseases
National Institutes of Health, Department of Health and Human Services
- Obligated
- $6,679,733
Award facts
- Assistance listing
- 93.855 Allergy and Infectious Diseases Research
- Completion date 88% complete
- Funding
-
- $6,019,555.00 Federal
- $660,178.00 Non-federal
- Place of performance
- Baltimore, MD 21201, USA
Award details come from USAspending.gov.
Description
- Abstract
- Plasmodium vivax threatens half of the world's population and is surprisingly resilient to on-going malaria elimination efforts, partially due to its unique characteristics and our poor understanding of its biology. Here, we propose to conduct state-of-the-art transcriptomic analyses using materials derived directly from cambodian patients to rigorously assess the importance of red blood cell polymorphisms, host immunity and parasite factors in modulating the efficacy of red blood cell invasion and P. Vivax intraerythrocytic development. Our studies will not only provide a better understanding of the fundamental molecular and cellular processes underlying blood stage P. Vivax infections but will also provide a solid foundation to develop better malaria vaccines against this important but understudied human pathogen.
Transactions
| Action | Federal | Non-federal | Date |
|---|---|---|---|
| Amendment | $154,170 | $0 | |
| Amendment | $530,121 | $0 | |
| Amendment | $530,121 | $0 | |
| Amendment | $154,170 | $0 | |
| Amendment | $154,170 | $0 | |
| Amendment | $536,141 | $0 | |
| Amendment | $536,141 | $0 | |
| Amendment | $691,533 | $0 | |
| Amendment | $706,316 | $0 | |
| Amendment | $706,316 | $0 | |
| Amendment | $660,178 | $0 | |
| Original award | $660,178 | $660,178 |
Show all 12
Subawards
| Subrecipient | Amount | Awarded |
|---|---|---|
| Institut Pasteur DU Cambodge | $154,170 | |
| University Of Georgia Research Foundation, Inc. | $14,647 | |
| Institut Pasteur DU Cambodge | $121,770 |
Quick answers
Who received award R01AI165483?
R01AI165483 was awarded to University Of Maryland, Baltimore by National Institute of Allergy and Infectious Diseases (National Institutes of Health) on June 8, 2022.
How much is award R01AI165483 worth?
$6,679,733 has been obligated on R01AI165483: $6,019,555 in federal funding and $660,178 in non-federal funding.
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