Project Grant R01AI147129

The Desmond Tutu Health Foundation received a $790,803 Project Grant from the National Institute of Allergy and Infectious Diseases within the Department of Health and Human Services. The grant supports the foundation's work to develop a method for gathering real-time data on factors influencing tuberculosis treatment adherence among men in South Africa. Specifically, the foundation will integrate modified ecological momentary assessments with medication event monitoring systems and assess the...

This $5.37 million project grant from the National Institutes of Health National Institute on Drug Abuse will fund the development of a context-aware digital adherence intervention called SMARTSTEPS to improve pre-exposure prophylaxis (PrEP) adherence among men who have sex with men with substance use disorder. The grant will support two phases. Phase I will inform the specification of an algorithm that utilizes digital phenotyping data from a smartphone app to anticipate non-adherence based...

Federal Cooperative Agreement Summary RE-EVALUATING THE DURATION IN CHILDREN OF TB TREATMENT (REDUCE TB): A PHASE 2 DURATION RANDOMIZED TRIAL The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $2.9 million Cooperative Agreement to the University of Wisconsin–Madison on September 19, 2025, to conduct a Phase 2 randomized clinical trial evaluating optimal treatment duration for drug-susceptible tuberculosis in children. The REDUCE TB trial will randomize pediatric...

Summary Fred Hutchinson Cancer Center received a $2.68 million Cooperative Agreement from the National Institute on Drug Abuse under the Drug Use and Addiction Research Programs (CFDA 93.279) awarded September 1, 2025, with completion targeted for July 31, 2030. The award funds development and evaluation of ACTIFY!, a mobile health application combining behavioral activation therapy with standard smoking cessation support. The project will conduct a fully-powered randomized controlled trial...

Federal Project Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded a $1.16M Project Grant to The Trustees of Columbia University in the City of New York (Health Sciences Division) on April 15, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279) to conduct a randomized controlled trial of the Sense2Quit App, a mobile health (mHealth) intervention designed specifically for people with HIV (PWH) who smoke. The research addresses the disproportionate smoking...

FAST-TB Project Grant Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $3.5 million through the Allergy and Infectious Diseases Research program (CFDA 93.855) to the University of California, San Francisco on June 8, 2026, to support the Facilitating Accelerated Science and Translation for TB Regimen Development (FAST-TB) initiative through May 31, 2031. This project grant delivers shared infrastructure and durable resources designed to accelerate the evaluation,...

FEND-TB Project Grant Summary Rutgers, The State University of New Jersey (RBHS-School of Nursing) received a $3.09 million Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded September 10, 2025, with a completion date of August 31, 2030. The grant supports the development and evaluation of tuberculosis (TB) diagnostic tools and drug susceptibility tests (DSTs) through a...

Federal Project Grant Award Summary: TB LATITUDE The Global Alliance For TB Drug Development Inc. (TB Alliance) received an $802,418 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded May 7, 2026, with an ultimate completion date of April 30, 2028. Under the TB LATITUDE (Long-Acting Treatment Innovation for Tuberculosis Drug Effectiveness) initiative, TB Alliance is developing...

STEPNET-ADAPT Project Grant Summary The University of California, San Diego received a $796,998 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), effective July 9, 2026, with a completion date of February 28, 2031. The award funds the STEPNET-ADAPT initiative, a sequential multiple assignment randomized trial (SMART) designed to develop and evaluate...

Project Summary: MISTR+ Study on Telehealth PrEP Delivery The National Institute of Allergy and Infectious Diseases (NIAID) awarded Emory University $1,273,269 on June 2, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct the MISTR+ study, which will operate through May 31, 2031. This project aims to establish an evidence base for telemedicine-delivered HIV pre-exposure prophylaxis (PrEP) and improve health outcomes for over 100,000 users of the largest...