Project Grant R01AI083229

The Desmond Tutu Health Foundation received a $790,803 Project Grant from the National Institute of Allergy and Infectious Diseases within the Department of Health and Human Services. The grant supports the foundation's work to develop a method for gathering real-time data on factors influencing tuberculosis treatment adherence among men in South Africa. Specifically, the foundation will integrate modified ecological momentary assessments with medication event monitoring systems and assess the...

This five-year, $813,838 project grant from the National Institute of Allergy and Infectious Diseases will fund research into the genetic and hormonal mechanisms underlying sex differences in tuberculosis (TB) and TB-HIV coinfection. The Johns Hopkins University will investigate how X chromosome complement and sex steroid hormones impact TB pathogenesis using cellular models, animal studies, and human samples. Researchers will utilize a novel four core genotype mouse model to differentiate the...

Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $842,888 to The Regents of the University of California, San Francisco under the Allergy and Infectious Diseases Research program (CFDA 93.855) on February 9, 2026, for a project investigating immunogenetic determinants of response to drug-susceptible tuberculosis treatment. The research will be conducted through January 31, 2031, and aims to identify host immunological and transcriptional...

The Defense Health Agency awarded a $215,429 Project Grant to The Global Alliance For TB Drug Development Inc. (TB Alliance) to investigate a host-directed proteolysis-targeting chimera (PROTAC) approach for targeting intracellular Mycobacterium tuberculosis. This two-year grant, running from July 2024 to July 2026, supports TB Alliance's research and development efforts to accelerate the development of new tuberculosis (TB) drugs and treatment regimens. The funding falls under the Military...

The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $4.76 million Project Grant to The Regents of the University of California, San Francisco under the Allergy and Infectious Diseases Research program (CFDA 93.855) to support the Rapid Research for Diagnostics Development in TB Network: Episode 2 (R2D2 TB Network II). Awarded on September 23, 2025, with a completion date of August 31, 2030, this initiative addresses critical gaps in tuberculosis (TB) diagnostics in...

Federal Project Grant Summary: FEND-TB Rutgers The State University of New Jersey, in partnership with the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), received a $3.09 million Project Grant awarded September 10, 2025, with a completion date of August 31, 2030. The FEND-TB initiative addresses critical gaps in tuberculosis (TB) diagnostics by establishing a consortium-based pipeline to support the...

Federal Project Grant Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $743,651 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to The Regents of the University of California, San Francisco, effective August 1, 2025, through July 31, 2030. The project focuses on developing and validating plasma cell-free RNA (cfRNA) biomarkers for tuberculosis diagnosis and treatment monitoring. The research team will conduct diagnostic...

Federal Grant Award Summary The Johns Hopkins University received a $1,299,500 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective July 1, 2025 through June 30, 2027. The award supports research to assess post-tuberculosis (TB) lung disease in TB patients with and without human immunodeficiency virus (HIV) coinfection using novel positron emission tomography (PET)-based imaging...

Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Boston Children's Hospital $489,500 under the Allergy and Infectious Diseases Research program (CFDA 93.855) to develop innovative human cellular models for studying tuberculosis (TB) infection and innate immune responses. The award, effective August 1, 2025, through July 31, 2027, funds the establishment of a physiological in vitro lung alveolar epithelial cell organoid model derived...

Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Columbia University's Health Sciences Division a $253,497 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) on September 9, 2025, with completion targeted for August 31, 2027. This initiative, titled "Mobilizing Innovative Strategies to Improve TB Diagnosis and Retention in the TB Care Cascade for Migrant Communities in New York City," will...