Project Grant R01AG098800
- Federal Grant Award Summary The University of Florida Division of Sponsored Research received a $103,969 Project Grant award from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), effective July 3, 2026, with a completion date of June 30, 2028. The award supports research investigating circadian epigenetic regulation of aging skeletal muscle and the impact of exercise on muscle maintenance. The research will generate comprehensive genome-wide, circadian...
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded the University of South Florida $3.297 million under the Aging Research program (CFDA 93.866) for a four-year project period (September 1, 2025 – August 31, 2029) to develop novel peptidomimetic biomaterials that inhibit amyloid-beta (Aβ42) aggregation in Alzheimer's disease. The research deliverables include the rational design and characterization of structurally related analogues to a lead compound that stabilizes Aβ...
- Federal Project Grant Summary Wake Forest University Health Sciences received a $599,623 Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), effective February 1, 2026, through January 31, 2031. The grant funds research investigating the synergistic effects of unacylated ghrelin (UNAG) combined with endurance exercise (EE) on sarcopenia and mobility loss in aging populations. The research project will examine how UNAG+EE enhances mitochondrial...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded a $439,739 Project Grant to the University of Florida, Division of Sponsored Research, effective June 1, 2026, through May 31, 2028, under the Aging Research program (CFDA 93.866). This R01 grant from an Early-Stage Investigator supports a longitudinal research study examining biobehavioral signatures of repetitive head impacts (RHI) at the intersection of aging and Alzheimer's disease (AD). The research will...
- Federal Grant Award Summary The University of Florida Division of Sponsored Research received a $730,938 Project Grant from the National Institute on Aging under the Aging Research program (CFDA 93.866), effective July 1, 2026 through May 31, 2031, to develop and test combinatorial rehabilitation treatments for individuals with amyotrophic lateral sclerosis (ALS). The project will deliver research-based protocols and clinical outcomes data demonstrating the efficacy of therapeutic acute...
- This federal Project Grant award of $2,358,537.00 from the National Institute on Aging (CFDA 93.866 - Aging Research) supports a research project titled "Epigenetic Aging, Cognitive Function and Exercise in Older Adults" at the University of Pittsburgh. The project aims to investigate the impact of exercise on epigenetic aging and its relationship to cognitive function, brain health, and Alzheimer's disease biomarkers in non-cognitively impaired older adults. The award period runs from...
- Federal Grant Award Summary The Buck Institute for Research on Aging received a $533,500 Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), awarded July 15, 2026, with completion targeted for June 30, 2028. This award supports research investigating the role of autonomic nervous system (ANS) innervation in muscle stem cell (MuSC) aging and its relationship to sarcopenia—age-related loss of skeletal muscle mass and function affecting 10-22% of...
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded a Project Grant of $427,625 to The Washington University Office of Sponsored Research Services, effective February 15, 2026, through January 31, 2028, under the Aging Research program (CFDA 93.866). This research initiative addresses intramuscular adipose tissue (IMAT) quality in aging populations through a dual-track investigative approach combining human clinical studies and mouse model research. The project delivers...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded Pennington Biomedical Research Center a $749,481 Project Grant (CFDA 93.866, Aging Research) effective January 1, 2026, through December 31, 2030, to conduct a lifestyle intervention research study. The project will deliver a 12-week randomized controlled feeding trial examining the effects of a low-energy-density diet combined with exercise on fat mass reduction, muscle function improvement, and energy deficit...
- Summary of Federal Project Grant Award The National Institute on Aging (under the Aging Research program, CFDA 93.866) awarded Posit Science Corp a $1,006,653 Project Grant on September 20, 2025, to develop and clinically evaluate the INHANCE-MCI (Improving Neurological Health with Acetylcholine via Neuroplasticity-based Computerized Exercise in Mild Cognitive Impairment) program through May 31, 2027. The award funds a prospective, double-blind, parallel-arm, active-controlled clinical trial...
The National Institute on Aging (NIA) awarded a $1,827,526 Project Grant on July 15, 2026, to the Florida Institute For Human & Machine Cognition Inc. (IHMC) under the Aging Research program (CFDA 93.866). The award funds the BOOST-X clinical trial, a research initiative designed to evaluate the efficacy of dietary nitrate supplementation in enhancing exercise-induced health benefits in older adults. The trial will examine whether increasing nitrate bioavailability through nutritional supplementation, when combined with prescribed endurance and resistance training aligned with Department of Health and Human Services weekly exercise guidelines, can augment improvements in cardiorespiratory fitness, functional muscle quality, vascular endothelial function, mitochondrial function, oxidative stress, and muscle inflammation. This five-year project runs through June 30, 2031, and represents the first trial to couple nitrate-rich supplementation with combined exercise training in a systematic evaluation of inter-individual response heterogeneity to exercise interventions in aging populations. The research addresses a critical gap in gerontological science by investigating mechanisms to maximize exercise responsiveness across diverse older adults, thereby reducing inter-individual variability in health outcomes and supporting the broader public health goal of leveraging exercise as a multipotent countermeasure to age-related decline. IHMC, a non-profit research organization headquartered in Pensacola, Florida, will conduct this biomedical research as part of the NIA's mission to support research directed toward understanding aging processes and preventing age-related diseases and functional decline.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.8m | 7/8/26 |